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    Small Molecule

    Small Molecule: Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.

    Webinars

    • SEP 02, 2015 | 3:00 PM
      Impact of the cobas Liat® Flu Assay on Clinical Decision Making in the Emergency Department Setting (Clade Study Group)
      Impact of the cobas Liat® Flu Assay on Clinical Decision Making...
      Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
      Speaker: Glen Hansen, PhD
      Presented at: Microbiology Virtual Event Series 2015
      1
      SEP 02, 2015 | 3:00 PM
      Fundamentals and Clinical Applications of Biofilms and Rapid Diagnostic Technique
      Fundamentals and Clinical Applications of Biofilms and Rapid Diagnostic...
      Biofilm is an ancient and preferred mode of growth for microbes with 99% of all microbes residing in a biofilm. Biofilm is characterized by a community of microbes (usually polymicrobial ofte...
      Speaker: Randall Wolcott, MD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 1:30 PM
      Bioburden and Biofilm Control in the Pharmaceutical Industry
      Bioburden and Biofilm Control in the Pharmaceutical Industry
      The Pharmaceutical Industry has a diverse set of products all with varying level of microbial risk to patients. On the low risk extreme there are topical pharmaceuticals on the other extreme...
      Speaker: Mark Pasmore, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 1:30 PM
      How Anthropogenic Chemicals are Altering the Microbial World
      How Anthropogenic Chemicals are Altering the Microbial World
      The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
      Speaker: Erica Hartmann, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 12:00 PM
      Polyamines in bacterial growth and biofilm formation
      Polyamines in bacterial growth and biofilm formation
      Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
      Speaker: Anthony Michael, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 12:00 PM
      DNASTAR Software for Assembly and Analysis of Microbial Genomes
      DNASTAR Software for Assembly and Analysis of Microbial Genomes
      DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data for key NGS workflows, including microbial genome assembly. The DNASTAR assembly software is...
      Speaker: Matthew Keyser, MS
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 10:30 AM
      Control Experiments for Reproducible Microbiome Research
      Control Experiments for Reproducible Microbiome Research
      Rapid advances in sequencing technology and spectroscopy have led to new measurements of the microbiome. Labs make choices based on their environment of interest and the questions they wish t...
      Speaker: J. Paul Brooks, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 10:30 AM
      Growing together:  Lessons learned from the characterization of the pediatric microbiome
      Growing together: Lessons learned from the characterization of...
      Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
      Speaker: Emily Hollister, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 9:00 AM
      Keynote: Immunology and the Microbiome
      Keynote: Immunology and the Microbiome
      The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
      Speaker: Jack Gilbert, BSc, PhD
      Presented at: Microbiology Virtual Event Series 2015
      10
      SEP 02, 2015 | 7:30 AM
      Keynote: The Science of Biofilm Control with Antimicrobial Agents
      Keynote: The Science of Biofilm Control with Antimicrobial Agents
      This presentation will discuss fundamental physical, chemical, and biological concepts important to understanding control of detrimental biofilms. Four phenomena that are important in the act...
      Speaker: Phil Stewart, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 6:00 AM
      Structure and Function of the Human Microbiome
      Structure and Function of the Human Microbiome
      Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
      Speaker: Curtis Huttenhower, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      SEP 02, 2015 | 6:00 AM
      Rapid Tests to Decipher Microbiome Function in Health and Disease
      Rapid Tests to Decipher Microbiome Function in Health and Disease
      Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
      Speaker: Anisha Kharkia, MS
      Presented at: Microbiology Virtual Event Series 2015
      10
      SEP 02, 2015 | 6:00 AM
      Simple, fast and accurate microbial identification by sequencing
      Simple, fast and accurate microbial identification by sequencing
      Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
      Speaker: Jane Luo, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      JUL 02, 2015 | 8:00 AM
      Exosome Biogenesis and the Budding of Proteins and Viruses
      Exosome Biogenesis and the Budding of Proteins and Viruses
      Exosomes are small secreted vesicles that have a diameter of ~50-200 nm. Exosomes are enriched for a specific subset of host-derived proteins, nucleic acids, lipids and carbohydrates, though ...
      Speaker: Stephen Gould, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      14 8
      APR 07, 2015 | 8:30 AM
      Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
      Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
      Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
      Speaker: Roberto Iacone, PhD , Brad Swanson, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      11 2
      DEC 16, 2014 | 8:00 AM
      Detection of RNAs with flow cytometry
      Detection of RNAs with flow cytometry
       Single-cell analysis is one of the most rapidly growing fields in biomedical research that is significantly expanding our understanding on the biologic characteristics of various diseases. F...
      Speaker: Filippos Porichis, PhD
      Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
      79
      OCT 30, 2014 | 1:30 PM
      Dissecting cancer signaling pathways with chemical scalpels
      Dissecting cancer signaling pathways with chemical scalpels
      Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
      Speaker: Nadya Tarasova, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      14
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 28, 2014 | 8:00 AM
      The identification of single nucleotide and structural variants in gene sequencing
      The identification of single nucleotide and structural variants...
      The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
      Speaker: Max van Min and Laurel Provencher
      Sponsored By: Revvity
      15
      OCT 16, 2014 | 8:00 AM
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
      Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
       Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
      Speaker: Scott D Stanley, PhD
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      26
      SEP 24, 2014 | 3:00 PM
      Site-directed ligand discovery for cryptic sites and other challenging targets
      Site-directed ligand discovery for cryptic sites and other challenging...
      Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
      Speaker: Michelle Arkin, PhD
      Presented at: Advances in Drug Discovery and Development
      20
      SEP 24, 2014 | 2:00 PM
      Targeting Lysine Acetylation in Cancer
      Targeting Lysine Acetylation in Cancer
      Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
      Speaker: Jay Bradner, MD
      Presented at: Advances in Drug Discovery and Development
      18
      SEP 24, 2014 | 12:00 PM
      Exploiting cell death for drug discovery
      Exploiting cell death for drug discovery
      Professor Stockwell will discuss the discovery of ferroptosis, a novel model of regulated but non-apoptotic cell death. He will describe how some tumors are sensitized to ferroptosis and may...
      Speaker: Brent Stockwell, PhD
      Presented at: Advances in Drug Discovery and Development
      22
      SEP 24, 2014 | 10:00 AM
      Keynote, The Promises and Challenges of Next-Generation Therapeutics
      Keynote, The Promises and Challenges of Next-Generation Therapeutics
      The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
      Speaker: Greg Verdine, PhD
      Presented at: Advances in Drug Discovery and Development
      14
    SEP 02, 2015 | 3:00 PM
    Impact of the cobas Liat® Flu Assay on Clinical Decision Making in the Emergency Department Setting (Clade Study Group)
    Impact of the cobas Liat® Flu Assay on Clinical Decision Making...
    Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectio...
    Speaker: Glen Hansen, PhD
    Presented at: Microbiology Virtual Event Series 2015
    1
    SEP 02, 2015 | 3:00 PM
    Fundamentals and Clinical Applications of Biofilms and Rapid Diagnostic Technique
    Fundamentals and Clinical Applications of Biofilms and Rapid Diagnostic...
    Biofilm is an ancient and preferred mode of growth for microbes with 99% of all microbes residing in a biofilm. Biofilm is characterized by a community of microbes (usually polymicrobial ofte...
    Speaker: Randall Wolcott, MD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 1:30 PM
    Bioburden and Biofilm Control in the Pharmaceutical Industry
    Bioburden and Biofilm Control in the Pharmaceutical Industry
    The Pharmaceutical Industry has a diverse set of products all with varying level of microbial risk to patients. On the low risk extreme there are topical pharmaceuticals on the other extreme...
    Speaker: Mark Pasmore, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 1:30 PM
    How Anthropogenic Chemicals are Altering the Microbial World
    How Anthropogenic Chemicals are Altering the Microbial World
    The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
    Speaker: Erica Hartmann, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
    SEP 02, 2015 | 12:00 PM
    Polyamines in bacterial growth and biofilm formation
    Polyamines in bacterial growth and biofilm formation
    Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
    Speaker: Anthony Michael, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
     
     
  • SEP 02, 2015 | 12:00 PM
    DNASTAR Software for Assembly and Analysis of Microbial Genomes
    DNASTAR Software for Assembly and Analysis of Microbial Genomes
    DNASTAR offers an integrated suite of software for accurate assembly and analysis of sequence data for key NGS workflows, including microbial genome assembly. The DNASTAR assembly software is...
    Speaker: Matthew Keyser, MS
    Presented at: Microbiology Virtual Event Series 2015
    3
    SEP 02, 2015 | 10:30 AM
    Control Experiments for Reproducible Microbiome Research
    Control Experiments for Reproducible Microbiome Research
    Rapid advances in sequencing technology and spectroscopy have led to new measurements of the microbiome. Labs make choices based on their environment of interest and the questions they wish t...
    Speaker: J. Paul Brooks, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 10:30 AM
    Growing together:  Lessons learned from the characterization of the pediatric microbiome
    Growing together: Lessons learned from the characterization of...
    Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
    Speaker: Emily Hollister, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 9:00 AM
    Keynote: Immunology and the Microbiome
    Keynote: Immunology and the Microbiome
    The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
    Speaker: Jack Gilbert, BSc, PhD
    Presented at: Microbiology Virtual Event Series 2015
    10
    SEP 02, 2015 | 7:30 AM
    Keynote: The Science of Biofilm Control with Antimicrobial Agents
    Keynote: The Science of Biofilm Control with Antimicrobial Agents
    This presentation will discuss fundamental physical, chemical, and biological concepts important to understanding control of detrimental biofilms. Four phenomena that are important in the act...
    Speaker: Phil Stewart, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
     
     
  • SEP 02, 2015 | 6:00 AM
    Structure and Function of the Human Microbiome
    Structure and Function of the Human Microbiome
    Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
    Speaker: Curtis Huttenhower, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
    SEP 02, 2015 | 6:00 AM
    Rapid Tests to Decipher Microbiome Function in Health and Disease
    Rapid Tests to Decipher Microbiome Function in Health and Disease
    Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
    Speaker: Anisha Kharkia, MS
    Presented at: Microbiology Virtual Event Series 2015
    10
    SEP 02, 2015 | 6:00 AM
    Simple, fast and accurate microbial identification by sequencing
    Simple, fast and accurate microbial identification by sequencing
    Managing microbial contaminants is critical during the manufacturing of biologics, food and beverage to ensure that products meet the high quality product standard as well as staying complian...
    Speaker: Jane Luo, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
    JUL 02, 2015 | 8:00 AM
    Exosome Biogenesis and the Budding of Proteins and Viruses
    Exosome Biogenesis and the Budding of Proteins and Viruses
    Exosomes are small secreted vesicles that have a diameter of ~50-200 nm. Exosomes are enriched for a specific subset of host-derived proteins, nucleic acids, lipids and carbohydrates, though ...
    Speaker: Stephen Gould, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    14 8
    APR 07, 2015 | 8:30 AM
    Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
    Diabetic Cardiomyopathy Modeling & Screening with iPSC Cardiomyocytes
    Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
    Speaker: Roberto Iacone, PhD , Brad Swanson, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    11 2
     
     
  • DEC 16, 2014 | 8:00 AM
    Detection of RNAs with flow cytometry
    Detection of RNAs with flow cytometry
     Single-cell analysis is one of the most rapidly growing fields in biomedical research that is significantly expanding our understanding on the biologic characteristics of various diseases. F...
    Speaker: Filippos Porichis, PhD
    Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
    79
    OCT 30, 2014 | 1:30 PM
    Dissecting cancer signaling pathways with chemical scalpels
    Dissecting cancer signaling pathways with chemical scalpels
    Advances in genomic research have led to identification of the majority of the drivers of tumor progression. However, our understanding of the molecular mechanisms propelling tumor growth is...
    Speaker: Nadya Tarasova, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    14
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 28, 2014 | 8:00 AM
    The identification of single nucleotide and structural variants in gene sequencing
    The identification of single nucleotide and structural variants...
    The TLA Technology constitutes a paradigm shift in targeted next generation sequencing (NGS). The TLA technology uses the physical proximity of nucleotides within a locus of interest as the b...
    Speaker: Max van Min and Laurel Provencher
    Sponsored By: Revvity
    15
    OCT 16, 2014 | 8:00 AM
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap MS for Equine Urine Analysis
    Comprehensive Anti-doping Detection using the Q Exactive Orbitrap...
     Equine anti-doping analysis is a changing and dynamic field of science. The constant introduction of new drugs and biopharmaceuticals present challenges to the integrity of sports. Anti-dopi...
    Speaker: Scott D Stanley, PhD
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    26
     
     
  • SEP 24, 2014 | 3:00 PM
    Site-directed ligand discovery for cryptic sites and other challenging targets
    Site-directed ligand discovery for cryptic sites and other challenging...
    Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
    Speaker: Michelle Arkin, PhD
    Presented at: Advances in Drug Discovery and Development
    20
    SEP 24, 2014 | 2:00 PM
    Targeting Lysine Acetylation in Cancer
    Targeting Lysine Acetylation in Cancer
    Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
    Speaker: Jay Bradner, MD
    Presented at: Advances in Drug Discovery and Development
    18
    SEP 24, 2014 | 12:00 PM
    Exploiting cell death for drug discovery
    Exploiting cell death for drug discovery
    Professor Stockwell will discuss the discovery of ferroptosis, a novel model of regulated but non-apoptotic cell death. He will describe how some tumors are sensitized to ferroptosis and may...
    Speaker: Brent Stockwell, PhD
    Presented at: Advances in Drug Discovery and Development
    22
    SEP 24, 2014 | 10:00 AM
    Keynote, The Promises and Challenges of Next-Generation Therapeutics
    Keynote, The Promises and Challenges of Next-Generation Therapeutics
    The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
    Speaker: Greg Verdine, PhD
    Presented at: Advances in Drug Discovery and Development
    14
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