Small Molecule: Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
DATE: June 14, 2016TIME: 8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
Library preparation for Nanopore sequencing is a very flexible process. There are many ways in which a sequencing template, or other analyte, can be presented to a nanopore for analysis. PCR...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
When facing throughput challenges, whether working with small molecules, glycans, and polar/charged analytes in general, a higher throughput solution is now available. Multiple nano-litre inj...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
DATE: October 7th, 2015TIME: 9am Pacific time, 12pm Eastern timeThe neuroscience field is rapidly evolving as both a burgeoning area for basic research (Parkinson’s, Alzheimer’s, ...
Micro RNAs (miRNAs) are small, naturally-occurring non-coding ribonucleic acids with sizes between 18 and 40 nucleotides (nts) that have been demonstrated to play a significant role in the re...
Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
Among the frontier challenges in chemistry in the 21st century are the interconnected goals of increasing control of chemical reactivity while synthesizing and diversifying complex molecules ...
Humans are colonized by vast numbers of symbiotic microorganisms whose metabolisms are inextricably intertwined with our own. To understand how chemical transformations performed by the human...
Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Consumer, Household, and Industrial (CH&I) formulations have increasingly driven towards more environmentally acceptable ingredients within water-based formulations, microbial control str...
Oxford Nanopore's MinION is a small, portable USB-powered sensing device which is powered by nanopore technology. It is adaptable to the analysis of DNA, RNA, proteins or small molecules, and...
In this talk, Sonia Shah interweaves history and original reportage to explore the origins of epidemics, drawing parallels between the story of cholera-one of history's most disruptive and de...
Over the past twenty years there has been an accelerated attack on the use of preservatives in cosmetics. This increased scrutiny of preservatives has forced cosmetic companies to change thei...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Healthcare-associated infections (HAIs) continue to be a considerable problem for hospitals and healthcare institutions that can adversely affect patient outcomes and impact the financial bot...
Preservatives have been under attacks by NGO's and their willing accomplishes-the media and the marketers of cosmetics. But with all their science fiction and negative statements, what are t...
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
DATE: June 14, 2016TIME: 8am Pacific time, 11am Eastern timeImproving systems for rapid small-scale protein purification and analysis in order to obtain sample numbers for statist...
Library preparation for Nanopore sequencing is a very flexible process. There are many ways in which a sequencing template, or other analyte, can be presented to a nanopore for analysis. PCR...
In the adult central nervous system (CNS) small populations of neurons are formed in the adult olfactory bulb and dentate gyrus of the hippocampus. In the adult hippocampus, newly born neuron...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
When facing throughput challenges, whether working with small molecules, glycans, and polar/charged analytes in general, a higher throughput solution is now available. Multiple nano-litre inj...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
DATE: October 7th, 2015TIME: 9am Pacific time, 12pm Eastern timeThe neuroscience field is rapidly evolving as both a burgeoning area for basic research (Parkinson’s, Alzheimer’s, ...
Micro RNAs (miRNAs) are small, naturally-occurring non-coding ribonucleic acids with sizes between 18 and 40 nucleotides (nts) that have been demonstrated to play a significant role in the re...
Surface plasmon resonance (SPR) is a sensitive, label-free technique that detects mass changes due to biomolecular interactions on a surface. This versatile method has been used to evaluate t...
Among the frontier challenges in chemistry in the 21st century are the interconnected goals of increasing control of chemical reactivity while synthesizing and diversifying complex molecules ...
Humans are colonized by vast numbers of symbiotic microorganisms whose metabolisms are inextricably intertwined with our own. To understand how chemical transformations performed by the human...
Recent evidence demonstrating the importance of structural complexity in advancing compounds to the clinic points to the need for enhancing small molecule screening collections with sp3-rich ...
As a computational scientist I have been fortunate to work with many collaborators to generate biological data to train and test my models. We are in a position with increasing amounts of dat...
Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
Natural preservation is often cited as effective and “safe” alternative to traditional synthetic preservative systems. However, the so-called natural preservatives bring a number...
Consumer, Household, and Industrial (CH&I) formulations have increasingly driven towards more environmentally acceptable ingredients within water-based formulations, microbial control str...
Oxford Nanopore's MinION is a small, portable USB-powered sensing device which is powered by nanopore technology. It is adaptable to the analysis of DNA, RNA, proteins or small molecules, and...
In this talk, Sonia Shah interweaves history and original reportage to explore the origins of epidemics, drawing parallels between the story of cholera-one of history's most disruptive and de...
Over the past twenty years there has been an accelerated attack on the use of preservatives in cosmetics. This increased scrutiny of preservatives has forced cosmetic companies to change thei...
Control of infection from methicillin resistant Staphylococcus aureus (MRSA) has been a healthcare focus for more than 50 years. One of the reasons that active surveillance testing (AST) for...
Healthcare-associated infections (HAIs) continue to be a considerable problem for hospitals and healthcare institutions that can adversely affect patient outcomes and impact the financial bot...
Preservatives have been under attacks by NGO's and their willing accomplishes-the media and the marketers of cosmetics. But with all their science fiction and negative statements, what are t...
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