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Small Molecule
Small Molecule: Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
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SEP 24, 2014 | 10:00 AM
The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...SEP 24, 2014 | 7:00 AM
Diseases caused by an excess of protein function can often be treated by small molecule inhibitors. In contrast, many diseases caused by missing proteins cannot be addressed with this classic...SEP 24, 2014 | 5:00 AM
Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...MAR 20, 2014 | 12:00 PM
Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...MAR 20, 2014 | 7:00 AM
Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...MAR 19, 2014 | 12:00 PM
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...MAR 19, 2014 | 9:00 AM
Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive a...NOV 08, 2013 | 12:00 PM
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...Speaker: Jaime Guidry Auvil, PhDOCT 23, 2013 | 12:00 PM
Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...Speaker: Len Neckers, PhDOCT 17, 2013 | 7:00 AM
RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...Speaker: Michaela Bowden, PhDAUG 21, 2013 | 11:00 AM
RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...Speaker: Alisa Jackson, Zach Smith, Mary Blair, Dave DelanoPresented at: Genetics and Genomics Virtual Event Series 2013
SEP 24, 2014 | 10:00 AM
The ever-quickening pace of breathtaking advances in our understanding of disease biology has implicitly promised a profusion of drugs that will dramatically improve human health and well-bei...
SEP 24, 2014 | 7:00 AM
Diseases caused by an excess of protein function can often be treated by small molecule inhibitors. In contrast, many diseases caused by missing proteins cannot be addressed with this classic...
SEP 24, 2014 | 5:00 AM
Since leaving Pfizer to go back to academia in 2007, Andrew Hopkins (University of Dundee, UK) has been a leading researcher in the search for new informatics and computational methods to imp...
MAR 20, 2014 | 12:00 PM
Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...
MAR 20, 2014 | 7:00 AM
Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
MAR 19, 2014 | 12:00 PM
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic Amyloid beta (Abeta)1-42 oligomers is proposed to underlie cognitive decline in Alzheimers disease (AD). Syn...
MAR 19, 2014 | 9:00 AM
Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive a...
NOV 08, 2013 | 12:00 PM
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
Speaker:
Jaime Guidry Auvil, PhD
OCT 23, 2013 | 12:00 PM
Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
Speaker:
Len Neckers, PhD
OCT 17, 2013 | 7:00 AM
RNA-Seq allows the simultaneous observation of gene expression levels, mutations in the coding sequences, splice variants and gene fusions, which are especially important in cancer studies. A...
Speaker:
Michaela Bowden, PhD
AUG 21, 2013 | 11:00 AM
RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...
Speaker:
Alisa Jackson, Zach Smith, Mary Blair, Dave Delano
Presented at: Genetics and Genomics Virtual Event Series 2013