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Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, th...
In recognition of World AIDS Day, we invite you to discover the innovative work being done to help end the HIV epidemic in some of the hardest hit areas in India. A diagnosis is the first st...
Pathology Perspective: Discover the critical need for genomic testing in cancer and explore the differences between traditional tissue biopsies and liquid genomic profiling. We'll dive i...
Myelodysplastic Syndrome (MDS) requires a complicated workup that can be supported by Artificial Intelligence (AI). Initial findings using AI have shown that MDS can be preliminarily identif...
Summary: Internal quality control is an integral process of laboratory testing. A clinical laboratory's coagulation quality control (QC) program is a critical component of its quality as...
Assessment for anti-dsDNA antibodies provides some of the most significant challenges in autoantibody serology testing. Anti-dsDNA antibodies are an important biomarker for systemic lupus er...
It is over half a century since haemoglobin A1c (HbA1c) was recognised by medical professionals; the importance of HbA1c to the long term health of people with diabetes was clearly demonstra...
Tissue microarray combines tens to hundreds paraffin-embedded specimens into a single paraffin block. It is a practical and highly effective tool for high-throughput analyses including valid...
Access to and experiences with healthcare continue to be inequitable worldwide even at the level of clinical laboratory testing. From building and sustaining a thriving, diverse workforce to...
This talk will describe the role of the clinical lab in advancing health equity. It will define the gaps in equitable access to lab testing and how that impacts patient care. We will also co...
Medical laboratories are an integral part of the healthcare system. They supply crucial diagnostic data that underpins disease detection, patient care, and public health management....
Despite an overall good performance on all laboratory procedures used to detect monoclonal (M) proteins or paraproteins, mis- or false-diagnoses have been seen using electrophoresis methods,...
Immunoassays and mass spectrometric assays are the two major methodologies in contemporary clinical chemistry laboratories. While immunoassays are highly automated and offer a faster turnaro...
Traumatic brain injury (TBI) is a widespread global health concern, impacting approximately 10 million individuals annually. Beyond the initial acute phase, TBI often results in enduring neu...
Interference in laboratory assays is a concern since it can positively or negatively influence test results, which can affect patient care. Interferents could be endogenous or exogenous comp...
This talk will provide an overview of our work in the design of self-assembled, functionalised peptide and protein nanoparticles, hydrogels and bio-interfaces for applications in healthcare....
Coronavirus Disease 2019 (COVID-19) has driven the use of nucleic acid testing technology in clinical testing. There is a growing need for point-of-care testing (POCT)......
CRISPR-based diagnostics offer rapid and highly sensitive detection of disease biomarkers. Their ease of use and compatibility with lateral-flow readouts make them suitable for point-of-care...
In this talk, I will introduce two new tools that we developed based on CRISPR-enabled gene regulation in bacteria, and one method based on P1 phagemid-enabled delivery of Cas9 nuclease. Fir...
Smartphone-based optical imaging and sensing devices are among the next-generation biosensors that have shown great potential to transform the field of point-of-care (POC) diagnostics....
Rare diseases pose unique challenges in the medical field, often affecting a small but vulnerable population with limited treatment options. The Rare Disease Challenge (RaDiChal) is a ground...
Programmable genome integration of large, diverse DNA cargo without DNA repair of exposed DNA double-strand breaks remains an unsolved challenge in genome editing. We present programmable ad...
Rather than being famous in gene editing field only, by revealing the collateral cleavage activity of Cas12a, Cas13a, Cas14 effectors, and more, Clustered Regularly Interspaced Short Palindr...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
Endonuclease Cas12a, as one key part of the CRISPR/Cas biotechnology, possessed a unique dual enzymatic function which has been widely used for various applications1. However, the limits tra...