Post-Translational Modification are crucial for controlling protein stability, localization, and conformation. It refers to the chemical changes that occur after a protein has been produced and is a key step in protein biosynthesis.
Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
Date: October 20, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Over the past three decades, baculovirus expression vector system (BEVS) has become one of the most powerful and robus...
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
Date: December 9, 2021 Time: 6:00am (PDT), 9:00 am (EDT) As the number of biotherapeutic candidates in development is increasing, the requirements of analytical tools to understand the molec...
Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
DATE: December 11, 2017TIME: 09:00am PST, 12:00pm ESTReproducibility is an important and ongoing topic of discussion within the scientific community. Although the reasons underlying the...
DATE: August 29th, 2017TIME: 9:00am PT, 12:00pm ET Antibodies are frequently produced from a cell line that has been screened to ensure the protein is expressed with th...
DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
DATE: November 17, 2016
TIME: 8:30am PT, 11:30am ET
The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
DATE: October 27, 2016
TIME: 9:00am PT, 12:00pm ET
The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasi...
DATE: September 22, 2016
TIME: 4:00am PT, 7:00am ET, 11:00am GMT
Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
Date: October 20, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Over the past three decades, baculovirus expression vector system (BEVS) has become one of the most powerful and robus...
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
Date: December 9, 2021 Time: 6:00am (PDT), 9:00 am (EDT) As the number of biotherapeutic candidates in development is increasing, the requirements of analytical tools to understand the molec...
Date: October 27, 2021 Time: 6:00 AM PDT, 9:00 AM EDT Etanercept is a recombinant Fc fusion protein therapeutic that has a complex distribution of post-translation modifications (PTM), such...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
The ExD Option, available for both new and existing Agilent instruments, offers superior electron fragmentation in combination with collision induced dissociation (CID) compared to other exi...
Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
DATE: October 30, 2018TIME: 10:00am PT, 1:00pm ET Identification and quantification of post-translational modifications (PTM) presents a unique challenge to proteomic studies...
The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
DATE: December 11, 2017TIME: 09:00am PST, 12:00pm ESTReproducibility is an important and ongoing topic of discussion within the scientific community. Although the reasons underlying the...
DATE: August 29th, 2017TIME: 9:00am PT, 12:00pm ET Antibodies are frequently produced from a cell line that has been screened to ensure the protein is expressed with th...
DATE: April 14, 2017TIME: 10:00AM PST, 1:00PM ET The study presented will represent the most comprehensive characterization of lipid changes in the context of aging and DR to d...
DATE: November 17, 2016
TIME: 8:30am PT, 11:30am ET
The complex interactions between transcription, translation, and post-translational modifications are hidden from view in typ...
DATE: October 27, 2016
TIME: 9:00am PT, 12:00pm ET
The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasi...
DATE: September 22, 2016
TIME: 4:00am PT, 7:00am ET, 11:00am GMT
Here, we present a novel approach that combines the principles of the western blot (protein separation by SDS-PAGE; ...
Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...