Nanoparticles are the building blocks of the new emerging field of nanotechnology that in broadest terms signifies the understanding and controlling of properties of matter at dimensions of roughly 1-100nm. Nanoparticles, as their unique nanosize, share the unique pharmacokinetic characteristics compared with the traditional small-molecule drugs.
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Determining the purity of LNPs loaded with nucleic acids can be challenging due to their size heterogeneity. Here, we present analytical ultracentrifugation (AUC) methods that use multiwavel...
DEC 07, 2023 | 10:00 AM
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Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, th...
AAVs and LNPs are complementary gene transfer systems with respect to immunogenicity, tissue tropism and types of nucleic acids, which can be delivered. AUC provides a wealth of orthogonal a...
Date: January 25, 2023 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) The field of proteomics is poised for a single-molecule revolution – enabling more comprehensive analysis of the...
Date: October 27, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) The Problem Buffer exchange is a critical step to developing optimal vectors and payloads. Compared to biologics, deve...
Date: June 30, 2022 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CEST) Flow Cytometry is a widely used technology that enables researchers to rapidly characterize thousands of individual cells...
Date: June 16, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Lipid-based nanoparticles (LNPs) are effective non-viral vectors for delivering messenger RNA products (mRNA), most notab...
The need for next-generation, broadly protective coronavirus vaccines is underscored by the accelerated pace at which human coronaviruses have been emerging, the evolution of the current pan...
Date: November 17, 2021 Time: 1:00am (PST), 9 am BST, 10 am CEST The growing list of nanoparticle payloads and carrier systems includes proteins, lipids, polymers, small molecules, and more,...
Date: October 20, 2021 Time: 8:00am (PDT), 11:00am (EDT) From transistors to LEDs, as device length scales trend downward, poor thermal dissipation increasingly leads to nanoscale hotspots t...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
Learning Objectives: 1. Explore the neuroinvasive potential of SARS-CoV-2 2. Learn about possible consequences of neuroinvasion of SARS-CoV-2 3. Identify neuroimmune responses against SARS-C...
Date: April 27, 2021 Time: 7:00am (PDT), 11:00am (EDT) Visualization is an important step to address complex biological questions in vivo. The imaging process can widen the perspective of an...
Date: February 11, 2021 Time: 8:00am (PST), 11:00am (EST) Getting answers on what’s in your precious AAV, LVV, or lipid nanoparticle (LNP) sample means wanting to use the lowest possib...
Ice formation is a global issue that poses serious challenges for many applications. Certain species in colder regions of the world have adapted to that climate by producing antifreeze (glyc...
DATE: October 15, 2020 TIME: 8am PDT, 11am EDT Density gradient centrifugation is an effective method for the isolation and purification of small particles. Hollow rotors capable of hosting...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...