Library preparation is the initial part of the procedure for next generation sequencing. During this step, DNA or RNA is fragmented and then adhered, or ligated, to the sequencing platform allowing for sample identification. In ligation-based library prep fragmentation and ligation occur in two separate steps while in tagmentation-based library prep fragmentation and ligation are completed in one step.
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DNA fragmentation is a critical step in preparing DNA libraries for short read-based protocols. The two primary methods are mechanical shearing (using acoustic technology like Covaris) and e...
RNA-Seq remains a critical and robust methodology in understanding cellular and organismal changes associated with development and disease. Advances in automation have helped reduce the cost...
In the era of advanced biotechnology, automation plays a crucial role in accelerating cancer research. Next-generation sequencing (NGS) technology has revolutionized cancer research, but lab...
Advancements in Next Generation Sequencing (NGS) are changing the genomics industry, favoring those with scale. Quest Diagnostics' clinical expertise, combined with our infrastructure, p...
JUL 25, 2023 | 8:00 PM
C.E. CREDITS
NEED ABSTRACT Learning Objectives Understand how the challenges of amplification from low input DNA, including single cells, can be overcome Discover why more researchers are using a next ge...
JUN 27, 2023 | 11:00 AM
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Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths, according to the World Health Organization. Many cancers can be cu...
Date: December 13, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeu...
Date: November 16, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Immunopeptides play an essential role in adaptive immunity by activating and ensuring T-cell specificity. Mass spectro...
Date: October 04, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The Miro Canvas is a new platform which enables full walkaway automation of complex next generation sequencing (NGS) s...
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
Date: June 09, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Thousands of researchers worldwide have utilized microfluidics technology from Standard BioTools for genomics application...
Wastewater samples are challenging substrates for nucleic acid extraction, and choice of extraction method will determine the success of downstream analysis. Extraction methods must be able...
Objective : Evaluation of EDTA-gel blood collection tubes from remote locations for NIPS (Non-invasive prenatal testing). Design: Paired comparisons Population: 61 pregnant women from Britis...
APR 19, 2022 | 1:30 PM
C.E. CREDITS
Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
Targeted sequencing has many applications in cancer biomarker research, carrier screening and inherited disorders, drug development, mitochondrial DNA variant detection, human ID and paterni...