Chromosome aberrations are changes in chromosome structure or number. Most aberrations are known as aneuploidies, or different numbers of chromosomes other than pairs (e.g., a trisomy is an aneuploidy with one extra chromosome and a monosomy has one fewer chromosome for a total of 1).
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Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
Learning Objectives: 1. Identify different kinds of genomic resources 2. Learn to apply the features available in genomic resources to cancer variant interpretation 3. Describe the importanc...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
DATE: November 28, 2018TIME: 7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
DATE: October 16, 2018TIME: 7:00m PDT, 10:00am EDT 22q11 Deletion Syndrome (22q11DS) is a genomic disorder caused by a microdeletion of chromosome 22 that occurs...
DATE: August 9, 2018TIME: 8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging...
DATE: December 5, 2017TIME: 10:00AM PT, 1:00PM ET Monoclonal Gammopathies (MG) are characterized by chromosomal aberration of B-cells or plasma cells resulting in benign or mal...
DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By: Prostate cancer is a complex disease with multiple tumors originating independent...
Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...