Aptamers are oligonucleotides or peptide molecules that bind specifically to a target molecule. They are used for both research and clinical applications such as bioimaging probes, therapeutic delivery vehicles, and controlled release mechanisms for drugs.
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Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
December 15, 2022 8:00 AM PST
Date: October 26, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Current protein biomarkers are only moderately predictive in identifying individuals with mild traumatic brain injury...
Date: December 9, 2020 Time: 7:00am (PST), 10:00am (EST) In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messen...
DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
NanoMIPs, often called “plastic antibodies”, are made using a proprietary self-assembly process where the template molecule is incubated with monomers, each of which is free in so...
An aptamer (also known as a synthetic antibody) is a stable DNA, RNA, or peptide ligand that binds with high affinity and specificity to targets such as small molecules, peptides, proteins, b...
CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
Reliable expression of recombinant proteins in human or CHO cells is essential for many aspects of biomedical research and drug development but is often hampered by low expression yields that...
SELEX is a process that selects DNA or RNA from a random library of sequences based on their affinity for a target molecule. These high affinity ligands, called apta...