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Antigen-specific T cells
T cells, a type of CD8 T cells (also called cytotoxic T lymphocyte) that are activated against a specific antigen. CD8 T cells identify and eliminate foreign cells, such as cancer cells or virus-infected cells. Antigen specific T cells are capable of identifying a specific antigen that is specific to the invading cells.
OCT 05, 2022 | 10:30 AM
Learning Objectives: 1. Classify the obstacles to successful manufacturing of antigen-specific T-cells in immunotherapy. 2. Highlight the effects of CD45RA+ subsets in expansion of antigen-s...
JUL 21, 2022 | 8:00 AM
Date: December 09, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Flow cytometry is a trusted method to monitor T cell phenotype, plasticity, and functionality in basic research as we...
JUL 12, 2022 | 8:00 AM
Date: July 12, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) Dendritic cells (DCs) are a heterogeneous population of myeloid immune cells that act as peripheral sentinels specializin...
MAY 12, 2022 | 8:00 AM
Date: May 12, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Cell culture is key for efficient and reliable T cell workflows, be it activation/ and expansion, T helper cell polarizati...
MAR 24, 2022 | 8:00 AM
Date: March 24, 2021 Time: 08:00am (PDT), 11:00pm (EDT) Simply enough, we want to treat our cells well. Afterall, we want them to tell us their stories in basic research or work for us in th...
MAR 01, 2022 | 10:00 AM
Date: March 01, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) The high mortality of COVID-19 is mostly attributed to acute respiratory distress syndrome (ARDS), whose histopathologic...
DEC 09, 2021 | 8:00 AM
Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
DEC 07, 2021 | 8:00 AM
Date: November 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) Analysis of SARS-CoV-2–specific T cells is important to understand their role during acute disease and in long-term protection...
DEC 02, 2021 | 8:00 AM
Date: December 2, 2021 Time: 8:00am (PDT), 11:00am (EDT) Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To ad...
NOV 10, 2021 | 10:30 AM
To prevent and treat SARS-CoV-2 infections, a comprehensive understanding of both the humoral and cellular immune responses is essential. One critical component to understanding the fundamen...
OCT 21, 2021 | 8:00 AM
DATE: October 21, 2021 TIME: 8:00am PDT Coronavirus disease 2019 (COVID-19) is a global health crisis caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and th...
OCT 07, 2021 | 11:55 PM
Summary: Cancer neoantigens are highly specific to the tumor, potently immunogenic and can be targeted by both vaccines and engineered cellular therapies. This talk will introduce the defini...
OCT 06, 2021 | 10:30 AM
Effective immunotherapy of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of suitable tumor-specific antigens. To address this challenge, we have combined high-throughput fl...
SEP 22, 2021 | 11:59 PM
T cells exquisitely discriminate between antigenic and self-peptide ligands presented on major histocompatibility complexes (pMHCs) despite subtle differences in affinities. This aspect of a...
SEP 08, 2021 | 12:00 AM
For centuries, humans have become infected with endemic circulating Coronaviruses (hCoV), typically repeatedly throughout life. To understand how these respiratory infections establish CD4 T...
JUN 09, 2021 | 8:00 AM
DATE: June 9, 2021 TIME: 8:00am PDT Analyzing antigen-specific T cells is essential to understand fundamental immunological processes in the contexts of immuno-oncology, infectious dise...
JUN 08, 2021 | 8:00 AM
Date: June 08, 2021 Time: 08:00am (PDT) COVID-19 displays high clinical variability, but what determines its severity is unclear. Analysis of antigen-specific T cell responses has contribu...
JUN 02, 2021 | 12:00 AM
Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
