Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
This presentation will discuss the use of the FDA EUA process to implement SARS-CoV-2 assays to address the COVID-19 pandemic. The use of a team-based approach, through an Incident Command s...
Background Protection from SARS-CoV-2 vaccines wanes over time and is compounded by emerging variants including Omicron subvariants. This study evaluated safety and immunogenicity of SARS-Co...
1. Identify 3 barriers to immune cell response to cancer 2. List 3 approaches to overcome immunosuppressive barriers to bolster the immune response to cancer 3. Explain how fusion proteins c...
During the first year of the SARS-CoV-2 pandemic, international monitoring of SARS-CoV-2 genomic RNA revealed that the virus accumulated roughly 2 mutations per month. Nonetheless, one nonsy...
NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
One significant challenge with SARS-CoV-2 wastewater monitoring is the lack of optimized and standardized sample processing steps, from sample collection to RNA detection. Viral concentratio...
One of the main challenges in cancer immunotherapy is the resistance to I-O therapies. Primary resistance can occur before treatment and acquired resistance can occur in patients who respond...
The risk of mortality from COVID-19 follows a sharp age gradient, with older populations facing a thousand fold higher risk of death upon infection than children. At the same time, the COVID...
Viruses and virally transmitted diseases have been impacting human health and well-being for hundreds of years. Some of our greatest scientific challenges and medical triumphs have involved...
Learning Objectives: 1. Discuss the value of infectious disease diagnostics. 2. Recognize the importance of home diagnostics. 3. Identify how better diagnostics leads to more resiliency to p...
Join me, an applied epidemiologist with boots on the ground, as we review key discoveries learned from the reopening of sports, entertainment and the arts. The four pillars of reopening incl...
Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
Multiplex immunofluorescence IHC is a powerful technique to address the increasing research needs in immuno-oncology to better understand the tumor microenvironment. In this webinar, we will...
Vaccination and infection are two different paths to immunity. Understanding human immune responses to SARS-CoV-2 RNA vaccines is of interest for a panoply of reasons. mRNA vaccines have dem...
Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while maintaining a high degree of specificity to prevent inappropriate activation (auto...
Learning Objectives: 1. Drug Repurposing Strategies for SARS-CoV2 2. Validation pipeline for SARS-CoV-2 antiviral 3. Outlook for SARS-CoV-2 therapeutics...
Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
SARS-CoV-2 spreads through airborne transmission. Aerosols containing live virus are dispersed when an infected person exhales and then continue to accumulate indoors, putting others at risk...
The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
We use COVID-19 cases, hospitalizations, and mortality data and a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental framework to model possible trajectories o...
PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in acute...