Follow a comprehensive curation of novel and significant discoveries in the fields of genetics and genomics by watching these webinars. Highlighted areas of interest in the fields of genetics and genomics include epigenetics, molecular genetics, hereditary disease, clinical genetics, population genetics, etc.
Learning Objectives: 1. Demonstrate the utility of long-read RNA-sequencing in studying alternative isoforms 2. Define the long-Split-seq approach to profiling the transcriptomes of single-c...
5-fluorouracil (5-FU) and its oral analog capecitabine are fluoropyrimidine chemotherapy agents used in several solid tumors. Approximately 5% of patients inherit diminished or null activity...
Infectious gastroenteritis is a disease caused by bacterial, viral, and parasitic pathogens in which the small and/or large intestines become severely inflamed. Because infectious gastroenter...
Esophageal adenocarcinoma [EAC] is the fastest growing in incidence cancer in the US over the last 25 years, while also having a 5 year survival of less than 20%. Barrett’s Esophagus [...
The introduction of improved, more cost efficient target capture technologies has accelerated the adoption of Whole Exome Sequencing (WES) in clinical diagnostics. The ability to provide mor...
Realizing the promise of Precision Medicine requires both a deep understanding of the landscape of genomic evidence and an understanding of the molecular drivers that influence all aspects o...
The personalized treatment of each cancer patient with targeted therapies selected based on our understanding of the molecular biology of cancer has been the long-standing goal of......
Follow us on a journey of single cell data exploration. See how you can Process, Analyze, Compare, and Contextualize, your results to identify novel biological relationships and drive new hy...
Historically, nasopharyngeal sampling has been considered the gold standard for the detection of most upper respiratory tract infections, however major medical and laboratory supply chain is...
Join this year's poster presenters in the Poster Hall during the Poster Networking Hour, Wednesday, September 6th, from 1:00 –2:00 PM PDT , to chat live about their posters and lat...
As part of Healthy Davis Together, we have implemented rapid, inexpensive, high throughput testing for SARS-Cov-2 using technology repurposed from the agricultural biotechnology sector. This...
In the field of oncology, the ability to select cells from a specific location or region within a tissue and analyze each discrete genome allows for the understanding of tumor heterogeneity....
Short tandem repeats (STRs) are gold-standard genetic loci used for source attribution of evidentiary material in legal matters. Their power lies in their high heterozygosity and large allel...
The CYP2D6 enzyme metabolizes approximately 25% of commonly used pharmaceuticals and is of intense pharmacogenetic interest. Polymorphisms in CYP2D6 can alter an individual’s response...
Class II Biosafety Cabinets (BSCs) are a staple in basic science laboratories. With many choices available, it can be difficult to select a BSC that provides the safest, smartest experience....
For infectious disease pathogen detection and research, real-time PCR enables reliable, sensitive, specific, and scalable results over slower culture-based methods...
The Genome in a Bottle Consortium has published benchmarks for variant calling, but some challenging medically-relevant genes have been partially or fully excluded due to mapping challenges,...
Precise diagnosis of neurodevelopmental disorders (NDDs), which often have genetic causes, is a challenging and important problem. Here we describe the results of a recent pilot study using...
The recent explosion in the sample sizes and diversity of omics assays has created exciting new opportunities for biomedical scientists. However, connecting these omics data types in an inte...
Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides important insigh...
Recurrently emerging SARS-CoV-2 variants of concern (VOC) present increasingly sophisticated immune escape strategies that fuel global infection rates, as exemplified by the raging B.1.1.529...
Many oncology patients do not receive the most effective targeted treatments because of challenges associated with implementation of a personalized medicine approach. Despite a lengthy histo...
The recent outbreak of the Coronavirus Disease 2019 (COVID-19) has spread all over the world and raised global concerns. Rapid and early detection of the novel coronavirus SARS-CoV-2, the ca...
My laboratory uses tools from pharmacology, genomics, and cell signaling to study two key aspects of cancer biology. First, we seek to understand how oncogenic signals, altered metabolic sta...
The All of Us (AoU) initiative aims to enhance personalized medical care by sequencing the genomes of over one million Americans of diverse ethnic backgrounds. To improve sequencing accuracy...
Do you have targets that are difficult to genotype? Are you starting new projects and looking for a fast convenient genotyping solution?Whether screening CRISPR clones, exploring pharmaco...
Characterization of rare cells remains a major challenge for the evaluation and understanding of key biological systems, such as circulating tumor cells (CTCs) from liquid biopsy, stem cells...