Translational Research: involves the application of knowledge gained through basic research to studies that could support the development of new products. For example, translational research in the field of medicine may involve using knowledge of the biology of a disease to identify and evaluate chemical compounds in disease models, with a view to selecting potential candidate drugs to advance into clinical trials.
Spatialomics leverages multiplex imaging to achieve translational profiling of tissue specimens by assessing the relative spatial orientations of biological structures with RNA and protein e...
Human cytomegalovirus (CMV) infection is common and usually results in a mild, non-specific illness in otherwise healthy individuals followed by asymptomatic latency. However, congenital CMV...
Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
Microorganisms have always been integral to natural circular processes in the environment. They serve an important role in converting complex biological molecules into central building block...
The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
Abstract Learning Objectives Define a tertiary lymphoid structure in human cancer Describe the tumor microenvironment factors that influence the formation of tertiary lymphoid structures Ide...
Date: April 26, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
Date: April 11, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Duchenne muscular dystrophy is caused by mutations in the dystrophin encoding DMD gene that disrupt the reading frame. M...
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
Next-generation sequencing can detect multiple driver oncogenes simultaneously, enabling the analysis of limited amounts of biopsied tissue samples. . Druggable driver mutations cover more t...
Next-generation sequencing can detect multiple driver oncogenes simultaneously, enabling the analysis of limited amounts of biopsied tissue samples. . Druggable driver mutations cover more t...
In this study, we evaluated the concordance of targeted sequencing results between paired ctDNA and tumor samples from early breast cancers scheduled for curative surgery with or without adj...
In this study, we evaluated the concordance of targeted sequencing results between paired ctDNA and tumor samples from early breast cancers scheduled for curative surgery with or without adj...
Date: March 23, 2023 Time: 8:00am (PDT), 11:00am (EDT), 8:00pm (CEST) Across clinical oncology applications, from molecular testing to cancer research the ability to identify potentially act...
Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical...
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
Spatialomics leverages multiplex imaging to achieve translational profiling of tissue specimens by assessing the relative spatial orientations of biological structures with RNA and protein e...
Human cytomegalovirus (CMV) infection is common and usually results in a mild, non-specific illness in otherwise healthy individuals followed by asymptomatic latency. However, congenital CMV...
Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
Microorganisms have always been integral to natural circular processes in the environment. They serve an important role in converting complex biological molecules into central building block...
The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
Abstract Learning Objectives Define a tertiary lymphoid structure in human cancer Describe the tumor microenvironment factors that influence the formation of tertiary lymphoid structures Ide...
Date: April 26, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the...
Date: April 25, 2023 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) The presynaptic protein alpha-synuclein (α-syn) is associated with Parkinson’s disease and Lewy body dementi...
Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
Date: April 11, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Duchenne muscular dystrophy is caused by mutations in the dystrophin encoding DMD gene that disrupt the reading frame. M...
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
Date: March 30, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join the Gibco Cell Culture Heroes webinar featuring Heather Beasley, PhD as she presents "SLC25A46 as a Novel Mitoc...
Next-generation sequencing can detect multiple driver oncogenes simultaneously, enabling the analysis of limited amounts of biopsied tissue samples. . Druggable driver mutations cover more t...
Next-generation sequencing can detect multiple driver oncogenes simultaneously, enabling the analysis of limited amounts of biopsied tissue samples. . Druggable driver mutations cover more t...
In this study, we evaluated the concordance of targeted sequencing results between paired ctDNA and tumor samples from early breast cancers scheduled for curative surgery with or without adj...
In this study, we evaluated the concordance of targeted sequencing results between paired ctDNA and tumor samples from early breast cancers scheduled for curative surgery with or without adj...
Date: March 23, 2023 Time: 8:00am (PDT), 11:00am (EDT), 8:00pm (CEST) Across clinical oncology applications, from molecular testing to cancer research the ability to identify potentially act...
Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
Animal models present a unique opportunity to understand molecular mechanisms of pathological changes involved in cognitive dysfunction in neurological disorders. However, most of the work f...
Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical...
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...