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    Translational Oncology

    Translational Oncology involves moving scientific discoveries made in a laboratory setting into clinical applications that enhance treatment efficacy and outcomes for cancer patients. Translational Oncology approaches include pre-clinical research, which can be done in an in vivo, in vitro, or ex vivo setting, before validating the laboratory findings with a clinical trial.

    Webinars

    • JUN 14, 2016 | 2:53 PM
      Testcast
      Testcast
      Testcast...
      Speaker: Jeffrey N Weitzel, MD
      Presented at: test of emergency broadcast system
      0
      MAY 12, 2016 | 12:00 PM
      Implementation of genomic assays for tumor genome profiling in a clinical laboratory setting
      Implementation of genomic assays for tumor genome profiling in...
      In order to realize the benefits of personalized cancer therapy, increasing demands are placed upon clinical laboratories to provide timely, comprehensive, clinically actionable, and analytic...
      Speaker: Sarah Murray, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      2
      MAY 04, 2016 | 9:00 AM
      Cell free methods for producing protein microarrays
      Cell free methods for producing protein microarrays
      Self-assembling protein microarrays arrays can be used to study protein-protein interactions, protein-drug interactions, search for enzyme substrates, and as tools to search for disease bioma...
      Speaker: Joshua LaBaer, MD, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      FEB 24, 2016 | 1:00 PM
      From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
      From genomics to precision medicine: Uncovering and manipulating...
      Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
      Speaker: Manolis Kellis, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 12:00 PM
      G-DOC Plus: A Data Science Platform for Precision Medicine Research
      G-DOC Plus: A Data Science Platform for Precision Medicine Research
      The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
      Speaker: Subha Madhavan, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 9:00 AM
      Keynote Presentation - Progress in the Precision Medicine Initiative
      Keynote Presentation - Progress in the Precision Medicine Initiative
      On January 20, 2015, President Obama announced the Precision Medicine Initiative® (PMI) (link is external) in his State of the Union address. Through advances in research, technology and...
      Speaker: Kathy Hudson, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 7:00 AM
      Precision Medicine Approaches and the Future of Drug Development in Oncology
      Precision Medicine Approaches and the Future of Drug Development...
      A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
      Speaker: Thomas Metcalfe
      Presented at: Precision Medicine Virtual Event Series 2016
      3
      FEB 04, 2016 | 10:30 AM
      Stressed out! The consequences of environmentally induced stress on mouse models
      Stressed out! The consequences of environmentally induced stress...
      The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
      Speaker: Brianna Gaskill, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 04, 2016 | 9:00 AM
      Keynote: The ARRIVE guidelines: Improving the design and reporting of animal research to optimize the reproducibility of animal studies
      Keynote: The ARRIVE guidelines: Improving the design and reporting...
      The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) is leading an initiative to improve the design and reporting of animal research. The ARRIVE (A...
      Speaker: Katie Lidster, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      FEB 04, 2016 | 6:00 AM
      Steps on the route to optimising experimental design, including teaching and conducting systematic reviews
      Steps on the route to optimising experimental design, including...
      A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
      Speaker: Derek Fry OBE, MA, D Phil, MB BCh , Rob de Vries, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 04, 2016 | 6:00 AM
      Improving methodological quality of animals experiments - are we doing all we can?
      Improving methodological quality of animals experiments - are...
      Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
      Speaker: Nuno Franco, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 3:00 PM
      Critical Appraisal of Animal Studies
      Critical Appraisal of Animal Studies
      Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
      Speaker: Annette O'Connor, BVSc, MVSc, DVSc, FACVSc
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 3:00 PM
      The Future of Preclinical Animal Models in Pharmaceutical Discovery and Development: How the Scientific 3Rs of Relevance, Robustness and Reproducibility are Critical
      The Future of Preclinical Animal Models in Pharmaceutical Discovery...
      Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
      Speaker: Jeffrey Everitt, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      4
      FEB 03, 2016 | 1:30 PM
      In-house development and implementation of surgical animal models
      In-house development and implementation of surgical animal models
      Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      FEB 03, 2016 | 12:00 PM
      Evaluating the results of animal studies by means of Meta Analysis
      Evaluating the results of animal studies by means of Meta Analysis
      Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
      Speaker: Carlijn Hooijmans, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      7
      FEB 03, 2016 | 9:00 AM
      Keynote: Risks of Bias in in vivo research - and what to do about them
      Keynote: Risks of Bias in in vivo research - and what to do about...
      Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
      Speaker: Malcolm Macleod BSc(Hons) MBChB PhD FRCP Ed
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 6:00 AM
      From the 3Rs to Systematic Reviews
      From the 3Rs to Systematic Reviews
      Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
      Speaker: Merel Ritskes-Hoitinga, DVM, PhD, Animal Welfare Officer, Dipl ECLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      JAN 15, 2016 | 4:00 AM
      Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
      Multiplex IHC and novel monoclonal antibodies as enabling tools...
      DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
      Speaker: Matthew Silver, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      10 1
      NOV 12, 2015 | 1:30 PM
      NGS in clinical research
      NGS in clinical research
      Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
      Speaker: Jennifer Fostel, MS
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      1
      NOV 12, 2015 | 10:30 AM
      Validation of Mass Spec Analytical Platforms and Proteomic Biomarkers: FDA perspective
      Validation of Mass Spec Analytical Platforms and Proteomic Biomarkers:...
      Basic research in Proteomics has led to new understanding of proteins’ contributions to health and disease, and has also driven the advancement of powerful analytical technologies used...
      Speaker: Doug Jeffery, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      2
      OCT 01, 2015 | 7:30 AM
      A Case Study for Immunotherapies and Targeted Therapies
      A Case Study for Immunotherapies and Targeted Therapies
      Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
      Speaker: Louise Perkins, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 10:30 AM
      The Evolving Role of Image-Guided Prostate Cancer Targeting and Ablation: Moving Towards Personalized Medicine
      The Evolving Role of Image-Guided Prostate Cancer Targeting and...
      The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
      Speaker: Rajan Gupta, MD , Thomas Polascik, MD , Stacy Loeb, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      0
      SEP 16, 2015 | 9:00 AM
      Transforming translational medicine for effective drug discovery
      Transforming translational medicine for effective drug discovery
      Learning Objectives for this presentation - (1) Understand how human genetics can contribute to drug discovery and development. (2) Understand the role of biomarkers and clinical proof-...
      Speaker: Robert Plenge
      Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
      3
      JUL 22, 2015 | 9:00 AM
      WEBINAR: Investigative in vitro Drug Toxicology with Human iPSC-derived Cardiomyocytes
      WEBINAR: Investigative in vitro Drug Toxicology with Human iPSC-derived...
      DATE: July 22, 2015TIME: 9:00AM PT, 12:00PM ETHuman induced pluripotent stem cells (iPSCs) bring human biology into pre-clinical aspects of drug discovery. iPSC-derived cardiomyocytes have em...
      Speaker: Blake Anson, PhD , Mathew Brock, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      10 1
    JUN 14, 2016 | 2:53 PM
    Testcast
    Testcast
    Testcast...
    Speaker: Jeffrey N Weitzel, MD
    Presented at: test of emergency broadcast system
    0
    MAY 12, 2016 | 12:00 PM
    Implementation of genomic assays for tumor genome profiling in a clinical laboratory setting
    Implementation of genomic assays for tumor genome profiling in...
    In order to realize the benefits of personalized cancer therapy, increasing demands are placed upon clinical laboratories to provide timely, comprehensive, clinically actionable, and analytic...
    Speaker: Sarah Murray, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    2
    MAY 04, 2016 | 9:00 AM
    Cell free methods for producing protein microarrays
    Cell free methods for producing protein microarrays
    Self-assembling protein microarrays arrays can be used to study protein-protein interactions, protein-drug interactions, search for enzyme substrates, and as tools to search for disease bioma...
    Speaker: Joshua LaBaer, MD, PhD
    Presented at: 2016 Gibco ExpressionWorld
    2
    FEB 24, 2016 | 1:00 PM
    From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
    From genomics to precision medicine: Uncovering and manipulating...
    Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
    Speaker: Manolis Kellis, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 12:00 PM
    G-DOC Plus: A Data Science Platform for Precision Medicine Research
    G-DOC Plus: A Data Science Platform for Precision Medicine Research
    The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
    Speaker: Subha Madhavan, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
     
     
  • FEB 24, 2016 | 9:00 AM
    Keynote Presentation - Progress in the Precision Medicine Initiative
    Keynote Presentation - Progress in the Precision Medicine Initiative
    On January 20, 2015, President Obama announced the Precision Medicine Initiative® (PMI) (link is external) in his State of the Union address. Through advances in research, technology and...
    Speaker: Kathy Hudson, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 7:00 AM
    Precision Medicine Approaches and the Future of Drug Development in Oncology
    Precision Medicine Approaches and the Future of Drug Development...
    A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
    Speaker: Thomas Metcalfe
    Presented at: Precision Medicine Virtual Event Series 2016
    3
    FEB 04, 2016 | 10:30 AM
    Stressed out! The consequences of environmentally induced stress on mouse models
    Stressed out! The consequences of environmentally induced stress...
    The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
    Speaker: Brianna Gaskill, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 04, 2016 | 9:00 AM
    Keynote: The ARRIVE guidelines: Improving the design and reporting of animal research to optimize the reproducibility of animal studies
    Keynote: The ARRIVE guidelines: Improving the design and reporting...
    The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) is leading an initiative to improve the design and reporting of animal research. The ARRIVE (A...
    Speaker: Katie Lidster, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    FEB 04, 2016 | 6:00 AM
    Steps on the route to optimising experimental design, including teaching and conducting systematic reviews
    Steps on the route to optimising experimental design, including...
    A number of elements come into the mix when trying to optimise experimental design. Among these are having clear objectives, setting up valid comparisons, knowing how to avoid bias during the...
    Speaker: Derek Fry OBE, MA, D Phil, MB BCh , Rob de Vries, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
     
     
  • FEB 04, 2016 | 6:00 AM
    Improving methodological quality of animals experiments - are we doing all we can?
    Improving methodological quality of animals experiments - are...
    Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
    Speaker: Nuno Franco, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 3:00 PM
    Critical Appraisal of Animal Studies
    Critical Appraisal of Animal Studies
    Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
    Speaker: Annette O'Connor, BVSc, MVSc, DVSc, FACVSc
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 3:00 PM
    The Future of Preclinical Animal Models in Pharmaceutical Discovery and Development: How the Scientific 3Rs of Relevance, Robustness and Reproducibility are Critical
    The Future of Preclinical Animal Models in Pharmaceutical Discovery...
    Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
    Speaker: Jeffrey Everitt, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    4
    FEB 03, 2016 | 1:30 PM
    In-house development and implementation of surgical animal models
    In-house development and implementation of surgical animal models
    Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    FEB 03, 2016 | 12:00 PM
    Evaluating the results of animal studies by means of Meta Analysis
    Evaluating the results of animal studies by means of Meta Analysis
    Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
    Speaker: Carlijn Hooijmans, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    7
     
     
  • FEB 03, 2016 | 9:00 AM
    Keynote: Risks of Bias in in vivo research - and what to do about them
    Keynote: Risks of Bias in in vivo research - and what to do about...
    Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
    Speaker: Malcolm Macleod BSc(Hons) MBChB PhD FRCP Ed
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 6:00 AM
    From the 3Rs to Systematic Reviews
    From the 3Rs to Systematic Reviews
    Why did we change focus from the 3Rs to Systematic Reviews? Questionnaires on the 3Rs have revealed that the 3R search gets no high priority and the 3R search process is never included in fun...
    Speaker: Merel Ritskes-Hoitinga, DVM, PhD, Animal Welfare Officer, Dipl ECLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    JAN 15, 2016 | 4:00 AM
    Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
    Multiplex IHC and novel monoclonal antibodies as enabling tools...
    DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
    Speaker: Matthew Silver, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    10 1
    NOV 12, 2015 | 1:30 PM
    NGS in clinical research
    NGS in clinical research
    Currently, next-generation sequencing is not only being used for basic discovery research but also in clinical settings for translational biomarker profiling and clinical research studies inc...
    Speaker: Jennifer Fostel, MS
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    1
    NOV 12, 2015 | 10:30 AM
    Validation of Mass Spec Analytical Platforms and Proteomic Biomarkers: FDA perspective
    Validation of Mass Spec Analytical Platforms and Proteomic Biomarkers:...
    Basic research in Proteomics has led to new understanding of proteins’ contributions to health and disease, and has also driven the advancement of powerful analytical technologies used...
    Speaker: Doug Jeffery, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    2
     
     
  • OCT 01, 2015 | 7:30 AM
    A Case Study for Immunotherapies and Targeted Therapies
    A Case Study for Immunotherapies and Targeted Therapies
    Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
    Speaker: Louise Perkins, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 10:30 AM
    The Evolving Role of Image-Guided Prostate Cancer Targeting and Ablation: Moving Towards Personalized Medicine
    The Evolving Role of Image-Guided Prostate Cancer Targeting and...
    The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
    Speaker: Rajan Gupta, MD , Thomas Polascik, MD , Stacy Loeb, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    0
    SEP 16, 2015 | 9:00 AM
    Transforming translational medicine for effective drug discovery
    Transforming translational medicine for effective drug discovery
    Learning Objectives for this presentation - (1) Understand how human genetics can contribute to drug discovery and development. (2) Understand the role of biomarkers and clinical proof-...
    Speaker: Robert Plenge
    Presented at: C&EN's Virtual Symposium: Advances in Drug Discovery and Development
    3
    JUL 22, 2015 | 9:00 AM
    WEBINAR: Investigative in vitro Drug Toxicology with Human iPSC-derived Cardiomyocytes
    WEBINAR: Investigative in vitro Drug Toxicology with Human iPSC-derived...
    DATE: July 22, 2015TIME: 9:00AM PT, 12:00PM ETHuman induced pluripotent stem cells (iPSCs) bring human biology into pre-clinical aspects of drug discovery. iPSC-derived cardiomyocytes have em...
    Speaker: Blake Anson, PhD , Mathew Brock, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    10 1
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