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Therapeutic protein characterization
Therapeutic proteins are specially designed for a particular clinical approach. Therapeutic proteins must be extensively characterized to detect molecular variants which can develop naturally or during the manufacturing or storage processes. Any modifications to the protein can impact the therapeutic efficacy and thus they must be closely monitored during development and administration.
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MAY 10, 2017 | 4:00 AM
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...APR 05, 2017 | 9:00 AM
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...MAR 15, 2017 | 7:30 AM
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...MAR 15, 2017 | 7:30 AM
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...FEB 22, 2017 | 9:00 AM
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...JAN 19, 2017 | 8:00 AM
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...NOV 09, 2016 | 9:00 AM
DATE: November 9th, 2016 TIME: 9:00 AM PT, 12:00 PM ET The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...OCT 19, 2016 | 8:00 AM
DATE: October 19th, 2016 TIME: 8:00 AM PT, 11:00 AM ET Comprehensive characterization of protein therapeutics through highly quantitative data is crucial in order to eliminate risk to pat...OCT 11, 2016 | 7:00 AM
DATE: October 11, 2016 TIME: 7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...OCT 05, 2016 | 10:30 AM
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...Speaker: Joseph Beechem, PhD , Alessandra Cesano, MD, PhDAUG 11, 2016 | 11:00 AM
DATE: August 11, 2016 TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...JUN 29, 2016 | 7:30 AM
Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...MAY 04, 2016 | 10:00 AM
The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...APR 11, 2016 | 9:00 AM
9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhDSponsored By: Zymo Research, Zymo ResearchAPR 04, 2016 | 8:00 AM
DATE: April 4, 2016 TIME: 8:00am Pacific time, 11:00am Eastern time The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...MAR 17, 2016 | 10:30 AM
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...FEB 24, 2016 | 1:00 PM
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...FEB 24, 2016 | 8:00 AM
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...FEB 02, 2016 | 9:00 AM
DATE: February 2nd, 2016 TIME: 9am pacific time, 12pm eastern time What is the most appropriate technology to empower your research? Next generation sequencing (NGS) for RN...Speaker: Sridar Chittur, PhD, MBA , Yesim Gökmen-Polar, PhDSponsored By: Affymetrix, AffymetrixNOV 18, 2015 | 8:00 AM
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...NOV 04, 2015 | 11:00 AM
DATE: November 4th, 2015 TIME: 11:00am Pacific time, 2:00pm Eastern time AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...SEP 30, 2015 | 1:30 PM
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...SEP 02, 2015 | 6:00 AM
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...AUG 13, 2015 | 8:00 AM
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...Speaker: Andrew Herr, PhDPresented at: Beckman Coulter Life Sciences Virtual Trade Show
Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
MAY 10, 2017 | 4:00 AM
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
APR 05, 2017 | 9:00 AM
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
MAR 15, 2017 | 7:30 AM
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
MAR 15, 2017 | 7:30 AM
Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
FEB 22, 2017 | 9:00 AM
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
JAN 19, 2017 | 8:00 AM
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
NOV 09, 2016 | 9:00 AM
DATE: November 9th, 2016
TIME: 9:00 AM PT, 12:00 PM ET
The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug di...
OCT 19, 2016 | 8:00 AM
DATE: October 19th, 2016
TIME: 8:00 AM PT, 11:00 AM ET
Comprehensive characterization of protein therapeutics through highly quantitative data is crucial in order to eliminate risk to pat...
OCT 11, 2016 | 7:00 AM
DATE: October 11, 2016
TIME: 7:00am PT, 10:00am ET
Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
OCT 05, 2016 | 10:30 AM
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
Speaker:
Joseph Beechem, PhD
, Alessandra Cesano, MD, PhD
AUG 11, 2016 | 11:00 AM
DATE: August 11, 2016
TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT
The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...
JUN 29, 2016 | 7:30 AM
Implementation of Capillary Electrophoresis (CE) technology in the biopharmaceutical industry is helping to characterize purity, heterogeneity, and identity of therapeutic...
MAY 04, 2016 | 10:00 AM
The ExpiCHO transient expression system allows for the high titer production of a broad range of recombinant proteins. Due to the high titers observed for many proteins in the ExpiCHO system,...
APR 11, 2016 | 9:00 AM
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
Speaker:
Peter Jones, Ph.D., D.Sc.
, Nandor Than, MD, PhD
Sponsored By: Zymo Research,
Zymo Research
APR 04, 2016 | 8:00 AM
DATE: April 4, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
The use of surface plasmon resonance to characterize protein:protein interactions is well established and has bee...
MAR 17, 2016 | 10:30 AM
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
FEB 24, 2016 | 1:00 PM
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
FEB 24, 2016 | 8:00 AM
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
FEB 02, 2016 | 9:00 AM
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Speaker:
Sridar Chittur, PhD, MBA
, Yesim Gökmen-Polar, PhD
Sponsored By: Affymetrix,
Affymetrix
NOV 18, 2015 | 8:00 AM
Nanoparticle drug delivery systems (nanoDDS) are among the most promising avenues for effective treatment of many disorders, accomplished by the targeted release of chemotherapeutics, peptide...
NOV 04, 2015 | 11:00 AM
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
SEP 30, 2015 | 1:30 PM
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
SEP 02, 2015 | 6:00 AM
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
AUG 13, 2015 | 8:00 AM
Analytical ultracentrifugation (AUC) is a powerful technique for analyzing fundamental characteristics of macromolecules in solution, including size and shape, assembly state, and degree of p...
Speaker:
Andrew Herr, PhD
Presented at: Beckman Coulter Life Sciences Virtual Trade Show
Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences