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    T cell functionality

    T cells, also called T lymphocytes, are an integral component of the adaptive immune system which seek out and eliminate foreign particles. Functions of T cells include killing infected host cells, activating other immune cells, producing and releasing immune messengers called cytokines into the body, and regulating the immune response. When T cell functionality is hindered by disease, genetics, or environment, the immune system could be at severe risk.

    Webinars

    • SEP 10, 2019 | 9:00 AM
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
      DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
      Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
      Sponsored By: Beckman Coulter Life Sciences
      13
      JUN 26, 2019 | 9:00 AM
      Sample Management vs. Inventory Management: What is the difference?
      Sample Management vs. Inventory Management: What is the difference?
      DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
      Speaker: Kathi Shea , Markus Albertini, PhD
      Sponsored By: Brooks Life Sciences
      6 2
      JUN 20, 2019 | 1:30 PM
      Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness at Insight Molecular Labs
      Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness...
      The practice of precision medicine utilizes advanced diagnostic tools to identify specific groups of patients on the basis of particular molecular characteristics, and guide their treatment w...
      Speaker: David Hout, PhD , Benjamin Chaffey, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      JUN 20, 2019 | 1:30 PM
      Rapid Variant Modeling in a Hospital Setting
      Rapid Variant Modeling in a Hospital Setting
      Implementing precision genomic medicine in the pediatric acute care setting has several challenges. First, the diagnosis must be made quickly. Second, the determination of pathogenicity mus...
      Speaker: Matthew Bainbridge, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 12:00 PM
      NGS Target Enrichment Solutions to Drive Discovery in Precision Medicine Research
      NGS Target Enrichment Solutions to Drive Discovery in Precision...
      The long term goal of our collaborative effort is to bring precision medicine to the practice of veterinary oncology, using the wealth of genomic data gathered in human cancers as a roadmap....
      Speaker: Duane Hassane, PhD , Guannan Wang, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      Sponsored By: Twist Bioscience
      2
      JUN 20, 2019 | 12:00 PM
      Tissue and cfDNA Rare Alleles: How Low Can We Go?
      Tissue and cfDNA Rare Alleles: How Low Can We Go?
      This talk will review successful efforts at Washington University to employ novel reagents and informatics to the problem of rare allele detection. I will discuss a published bakeoff of in si...
      Speaker: Seth Crosby, MD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 12:00 PM
      Antiplatelet Agents for Secondary Stroke Prevention - Can We Be More Precise?
      Antiplatelet Agents for Secondary Stroke Prevention - Can We Be...
      Clopidogrel, an antiplatelet agent frequently used for secondary stroke prevention, is a prodrug that requires both sufficient intestinal absorption and hepatic modification to produce its ac...
      Speaker: Karen Albright, DO, PhD, MPH
      Presented at: Precision Medicine Virtual Event Series 2019
      2
      JUN 20, 2019 | 10:30 AM
      The Massively Parallel Sequencing (MPS) Revolution
      The Massively Parallel Sequencing (MPS) Revolution
      The development of automated DNA sequencers utilizing Sanger sequencing and capillary electrophoresis made it possible to develop the first draft sequences of the human genome. The cost of do...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 10:30 AM
      Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation Enabling Deeper Understanding of Somatic Alterations that Contribute to Cancer Initiation, Progression and Recurrence
      Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation...
      Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
      Speaker: Beate Litzenburger, Ph.D. , Raed Samara, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      JUN 20, 2019 | 10:30 AM
      Outlier Kinases as Targets for Precision Therapy
      Outlier Kinases as Targets for Precision Therapy
      In this presentation, Dr. Kothari will provide an overview of the Precision Medicine Initiative from NIH and how NGS technologies have helped the researchers to look deep inside the human tra...
      Speaker: Vishal Kothari, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 9:00 AM
      Precision Medicine & Health in Action: Practicing an N-of-1 Approach in the Clinic
      Precision Medicine & Health in Action: Practicing an N-of-1 Approach...
      The NIH put Precision Medicine on the map as a revolutionary way to manage disease, delivering the right treatment, to the right patient, at the right time. But what does Precision Medicine r...
      Speaker: Florence Comite, MD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 9:00 AM
      Keynote Presentation: Transforming Drug Discovery with Precision Medicine
      Keynote Presentation: Transforming Drug Discovery with Precision...
      Recent advances in genomic technologies have revealed enormous complexities and uniqueness of human physiology. Although enormous efforts are being made to apply this knowledge to enhance the...
      Speaker: Khyati Shah, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 6:00 AM
      Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
      Connecting Genetic and Transcriptional Variation in Acute Myeloid...
      Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
      Speaker: Stephen Williams, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      2
      JUN 20, 2019 | 6:00 AM
      See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
      See Further: Expanded Carrier Screening Tools That Take You From...
      Inherited disorders affect millions of people globally. These diseases significantly impact lives of patients and their families, and in addition, also results in substantial socio-economic i...
      Speaker: Raed Samara, PhD , Rupert Yip, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      MAY 30, 2019 | 1:30 PM
      Hybrid Tissue-Chips:  Modeling Drug Delivery and Disease with Novel Microfluidics for Living Tissue
      Hybrid Tissue-Chips: Modeling Drug Delivery and Disease with...
      Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
      Speaker: Rebecca Pompano, PhD
      Presented at: Laboratory Testing & Automation Virtual Event Series 2019
      2
      MAY 30, 2019 | 9:00 AM
      Lab on a Chip Technologies for Drug Discovery
      Lab on a Chip Technologies for Drug Discovery
      In this seminar, Dr Elvira will talk about the use of droplet microfluidic technologies for drug discovery. Initially, she will discuss the fundamental concepts of droplet microfluidic techno...
      Speaker: Katherine Elvira, MSci, PhD, ARCS
      Presented at: Laboratory Testing & Automation Virtual Event Series 2019
      1
      MAY 21, 2019 | 7:00 AM
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
      Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
      DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
      Speaker: Eric Shifrut, PhD
      Sponsored By: Thermo Fisher Scientific - Invitrogen
      10 1
      APR 11, 2019 | 10:00 AM
      Downstream Processing Challenges in Cell Therapy Manufacturing
      Downstream Processing Challenges in Cell Therapy Manufacturing
      DATE: April 11, 2019TIME: 10:00 AM PSTWith the recent FDA approval of the CAR-T cell therapies Kymriah® from Novartis and Yescarta® from Kite Pharma there has been a renewed i...
      Speaker: Jim Beltzer, MS, PhD , Geoffrey Uhl, MBA, BS
      Sponsored By: TERUMO BCT
      9 1
      FEB 27, 2019 | 3:00 PM
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
      Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
      In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
      Speaker: Jagath Reddy Junutula, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      DEC 12, 2018 | 8:00 AM
      Evolution in the Manufacturing of Cellular Therapies- lessons learned and current solutions
      Evolution in the Manufacturing of Cellular Therapies- lessons...
      DATE: December 012, 2018TIME: 08:00 PSTImmunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy,...
      Speaker: Neil Kayal
      Sponsored By: Beckman Coulter Life Sciences
      5
      DEC 06, 2018 | 9:00 AM
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
      DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      NOV 29, 2018 | 9:00 AM
      An overview of primary immune deficiency disorders (PID) and laboratory testing for PID
      An overview of primary immune deficiency disorders (PID) and laboratory...
      DATE: November 29, 2018TIME:  9:00AM PDTAn overview of primary immune deficiency disorders (PID) and laboratory testing for PIDPrimary immune deficiencies (PIDs), oth...
      Speaker: Vijaya Knight, MD, PhD, (D)ABMLI
      Sponsored By: Binding Site
      10
      NOV 01, 2018 | 12:00 AM
      Real-time Live-cell Analysis for Immunologists
      Real-time Live-cell Analysis for Immunologists
      Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
      Speaker: Del Trezise, PhD
      Presented at: Dimension of Time: From Culture to Assay
      2
    SEP 10, 2019 | 9:00 AM
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
    DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
    Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
    Sponsored By: Beckman Coulter Life Sciences
    13
    JUN 26, 2019 | 9:00 AM
    Sample Management vs. Inventory Management: What is the difference?
    Sample Management vs. Inventory Management: What is the difference?
    DATE: June 26, 2019TIME: 9:00am PDT, 12:00pm EDT An excessive number of software solutions are available to help manage your clinical, biobank, or biorepository sample inform...
    Speaker: Kathi Shea , Markus Albertini, PhD
    Sponsored By: Brooks Life Sciences
    6 2
    JUN 20, 2019 | 1:30 PM
    Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness at Insight Molecular Labs
    Introducing the therascreen FGFR RGQ RT-PCR Kit and Day-One Readiness...
    The practice of precision medicine utilizes advanced diagnostic tools to identify specific groups of patients on the basis of particular molecular characteristics, and guide their treatment w...
    Speaker: David Hout, PhD , Benjamin Chaffey, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    JUN 20, 2019 | 1:30 PM
    Rapid Variant Modeling in a Hospital Setting
    Rapid Variant Modeling in a Hospital Setting
    Implementing precision genomic medicine in the pediatric acute care setting has several challenges. First, the diagnosis must be made quickly. Second, the determination of pathogenicity mus...
    Speaker: Matthew Bainbridge, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 12:00 PM
    NGS Target Enrichment Solutions to Drive Discovery in Precision Medicine Research
    NGS Target Enrichment Solutions to Drive Discovery in Precision...
    The long term goal of our collaborative effort is to bring precision medicine to the practice of veterinary oncology, using the wealth of genomic data gathered in human cancers as a roadmap....
    Speaker: Duane Hassane, PhD , Guannan Wang, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    Sponsored By: Twist Bioscience
    2
     
     
  • JUN 20, 2019 | 12:00 PM
    Tissue and cfDNA Rare Alleles: How Low Can We Go?
    Tissue and cfDNA Rare Alleles: How Low Can We Go?
    This talk will review successful efforts at Washington University to employ novel reagents and informatics to the problem of rare allele detection. I will discuss a published bakeoff of in si...
    Speaker: Seth Crosby, MD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 12:00 PM
    Antiplatelet Agents for Secondary Stroke Prevention - Can We Be More Precise?
    Antiplatelet Agents for Secondary Stroke Prevention - Can We Be...
    Clopidogrel, an antiplatelet agent frequently used for secondary stroke prevention, is a prodrug that requires both sufficient intestinal absorption and hepatic modification to produce its ac...
    Speaker: Karen Albright, DO, PhD, MPH
    Presented at: Precision Medicine Virtual Event Series 2019
    2
    JUN 20, 2019 | 10:30 AM
    The Massively Parallel Sequencing (MPS) Revolution
    The Massively Parallel Sequencing (MPS) Revolution
    The development of automated DNA sequencers utilizing Sanger sequencing and capillary electrophoresis made it possible to develop the first draft sequences of the human genome. The cost of do...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 10:30 AM
    Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation Enabling Deeper Understanding of Somatic Alterations that Contribute to Cancer Initiation, Progression and Recurrence
    Beyond the Score: Tools for Pan-Biomarker Analysis and TMB Estimation...
    Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
    Speaker: Beate Litzenburger, Ph.D. , Raed Samara, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    JUN 20, 2019 | 10:30 AM
    Outlier Kinases as Targets for Precision Therapy
    Outlier Kinases as Targets for Precision Therapy
    In this presentation, Dr. Kothari will provide an overview of the Precision Medicine Initiative from NIH and how NGS technologies have helped the researchers to look deep inside the human tra...
    Speaker: Vishal Kothari, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
     
     
  • JUN 20, 2019 | 9:00 AM
    Precision Medicine & Health in Action: Practicing an N-of-1 Approach in the Clinic
    Precision Medicine & Health in Action: Practicing an N-of-1 Approach...
    The NIH put Precision Medicine on the map as a revolutionary way to manage disease, delivering the right treatment, to the right patient, at the right time. But what does Precision Medicine r...
    Speaker: Florence Comite, MD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 9:00 AM
    Keynote Presentation: Transforming Drug Discovery with Precision Medicine
    Keynote Presentation: Transforming Drug Discovery with Precision...
    Recent advances in genomic technologies have revealed enormous complexities and uniqueness of human physiology. Although enormous efforts are being made to apply this knowledge to enhance the...
    Speaker: Khyati Shah, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 6:00 AM
    Connecting Genetic and Transcriptional Variation in Acute Myeloid Leukemia at Single-Cell Resolution
    Connecting Genetic and Transcriptional Variation in Acute Myeloid...
    Virtually all tumors are genetically heterogeneous, containing subclonal populations of cells that are defined by distinct mutations. Subclones can have unique phenotypes that influence disea...
    Speaker: Stephen Williams, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    2
    JUN 20, 2019 | 6:00 AM
    See Further: Expanded Carrier Screening Tools That Take You From Sample to Insight
    See Further: Expanded Carrier Screening Tools That Take You From...
    Inherited disorders affect millions of people globally. These diseases significantly impact lives of patients and their families, and in addition, also results in substantial socio-economic i...
    Speaker: Raed Samara, PhD , Rupert Yip, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    MAY 30, 2019 | 1:30 PM
    Hybrid Tissue-Chips:  Modeling Drug Delivery and Disease with Novel Microfluidics for Living Tissue
    Hybrid Tissue-Chips: Modeling Drug Delivery and Disease with...
    Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
    Speaker: Rebecca Pompano, PhD
    Presented at: Laboratory Testing & Automation Virtual Event Series 2019
    2
     
     
  • MAY 30, 2019 | 9:00 AM
    Lab on a Chip Technologies for Drug Discovery
    Lab on a Chip Technologies for Drug Discovery
    In this seminar, Dr Elvira will talk about the use of droplet microfluidic technologies for drug discovery. Initially, she will discuss the fundamental concepts of droplet microfluidic techno...
    Speaker: Katherine Elvira, MSci, PhD, ARCS
    Presented at: Laboratory Testing & Automation Virtual Event Series 2019
    1
    MAY 21, 2019 | 7:00 AM
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
    Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key...
    DATE: May 21, 2019TIMEL 7:00am PT, 10:00am ET Human T cells are central effectors of immunity and cancer immunotherapy. CRISPR-based functional studies in T cells could prioriti...
    Speaker: Eric Shifrut, PhD
    Sponsored By: Thermo Fisher Scientific - Invitrogen
    10 1
    APR 11, 2019 | 10:00 AM
    Downstream Processing Challenges in Cell Therapy Manufacturing
    Downstream Processing Challenges in Cell Therapy Manufacturing
    DATE: April 11, 2019TIME: 10:00 AM PSTWith the recent FDA approval of the CAR-T cell therapies Kymriah® from Novartis and Yescarta® from Kite Pharma there has been a renewed i...
    Speaker: Jim Beltzer, MS, PhD , Geoffrey Uhl, MBA, BS
    Sponsored By: TERUMO BCT
    9 1
    FEB 27, 2019 | 3:00 PM
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug Conjugates
    Targeted Cancer Chemotherapy: Developing NextGen Antibody-Drug...
    In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
    Speaker: Jagath Reddy Junutula, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
     
     
  • DEC 12, 2018 | 8:00 AM
    Evolution in the Manufacturing of Cellular Therapies- lessons learned and current solutions
    Evolution in the Manufacturing of Cellular Therapies- lessons...
    DATE: December 012, 2018TIME: 08:00 PSTImmunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy,...
    Speaker: Neil Kayal
    Sponsored By: Beckman Coulter Life Sciences
    5
    DEC 06, 2018 | 9:00 AM
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    Cell and Gene Therapy Solutions: Enabling PSC Translation Workflows
    DATE:   December 6, 2018TIME:    9:00am PST, 12:00pm EST Induced pluripotent stem cells (iPSC) intended for translational applications need to be of...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    NOV 29, 2018 | 9:00 AM
    An overview of primary immune deficiency disorders (PID) and laboratory testing for PID
    An overview of primary immune deficiency disorders (PID) and laboratory...
    DATE: November 29, 2018TIME:  9:00AM PDTAn overview of primary immune deficiency disorders (PID) and laboratory testing for PIDPrimary immune deficiencies (PIDs), oth...
    Speaker: Vijaya Knight, MD, PhD, (D)ABMLI
    Sponsored By: Binding Site
    10
    NOV 01, 2018 | 12:00 AM
    Real-time Live-cell Analysis for Immunologists
    Real-time Live-cell Analysis for Immunologists
    Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
    Speaker: Del Trezise, PhD
    Presented at: Dimension of Time: From Culture to Assay
    2
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