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    T cell functionality

    T cells, also called T lymphocytes, are an integral component of the adaptive immune system which seek out and eliminate foreign particles. Functions of T cells include killing infected host cells, activating other immune cells, producing and releasing immune messengers called cytokines into the body, and regulating the immune response. When T cell functionality is hindered by disease, genetics, or environment, the immune system could be at severe risk.

    Webinars

    • APR 29, 2020 | 6:00 AM
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
      ...
      Speaker: Christian Regenbrecht, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 23, 2020 | 9:00 AM
      Keynote Presentation: Individualized Health
      Keynote Presentation: Individualized Health
      Learning Objectives: 1. What is wrong with healthcare today 2. What kinds of omics and wearables data can be used to best predict disease risk and manage health...
      Speaker: Michael Snyder, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Clinical Applications of Estrogen Metabolism Genetic Testing: Improving Estrogen Health, Preventing Breast Cancer and Prescribing Estrogenic Medications with Precision
      Clinical Applications of Estrogen Metabolism Genetic Testing:...
      Estrogen metabolism is the ability to favorably excrete potentially toxic estrogens through urine and sweat. Impaired estrogen metabolism is associated with Endometriosis and Polycystic Ovar...
      Speaker: T.J. Hills
      Presented at: Genetics Week Virtual Event Series 2020
      3 1
      APR 22, 2020 | 12:00 AM
      Priming the Precision Medicine Pipeline: New Models for Applied Genomics Education
      Priming the Precision Medicine Pipeline: New Models for Applied...
      As genomics plays an ever expanding role in healthcare and research, educational programs focused on applied genomics have not kept pace with the demand for trained students. In this talk, w...
      Speaker: Barbara Kraatz Fortini, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
      Long-range technologies resolve complex genomic regions overlooked...
      Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
      Speaker: Mark Ebbert, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 7:30 AM
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
      Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
      Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
      Speaker: Scott Soderling, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: CasTag Biosciences
      1 1
      APR 21, 2020 | 12:00 AM
      Single cell gene expression: new insights through the lens of full length mRNA isoform resolution
      Single cell gene expression: new insights through the lens of...
      Single cell RNA sequencing (scRNA-seq) emerged to characterize gene expression differences between individual cells, allowing a higher resolution look at mRNA abundance than bulk RNA- seq. H...
      Speaker: Jason Underwood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      APR 08, 2020 | 12:00 AM
      Collaborative Education for Talent of the Future
      Collaborative Education for Talent of the Future
      Strong performance for a Facility of the Future for the Life Sciences industry requires more than optimal manufacturing process development and facility design. The sector encompasses a dive...
      Speaker: Sue Behrens
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      The NISTmAb and Related Biopharmaceutical Resources
      The NISTmAb and Related Biopharmaceutical Resources
      The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
      Speaker: John Schiel, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
      There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
      Speaker: David Schaffer, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      2
      APR 02, 2020 | 8:00 AM
      Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
      Bionano Genome Imaging unravels complex structural rearrangements...
      DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
      Speaker: Eric Letouzé, PhD
      Sponsored By: Bionano
      14
      MAR 26, 2020 | 9:00 AM
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
      Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
      DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
      Speaker: Namritha Ravinder
      Sponsored By: Thermo Fisher Scientific - Invitrogen
      7
      MAR 11, 2020 | 10:30 AM
      Innate immunity in chronic neurodegeneration
      Innate immunity in chronic neurodegeneration
      The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
      Speaker: Michael Heneka, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      MAR 11, 2020 | 6:00 AM
      PANEL: The Neural Control of Locomotion, an Integrative Approach
      PANEL: The Neural Control of Locomotion, an Integrative Approach
      The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
      Speaker: Michael Dickinson, PhD , Anthony Azevedo, PhD , Clare Howard, PhD , Luke Brezovec , Sasha Rayshubskiy , Emily Palmer
      Presented at: Neuroscience Virtual Event Series 2020
      1
      FEB 25, 2020 | 10:00 AM
      Avances en la Tecnología del Diferencial de Glóbulos Blancos
      Avances en la Tecnología del Diferencial de Glóbulos Blancos
      DATE: 25 Febrero 2020 TIME: 13:00 COT, 10:00 PST Los desarrollos tecnológicos en analizadores automatizados de Hematología continúan transformando el laboratorio de Hema...
      Speaker: Don Wright
      Sponsored By: Abbott
      5 1
      JAN 01, 2020 | 6:00 AM
      Microphysiological Systems for Human Focused Drug Discovery
      Microphysiological Systems for Human Focused Drug Discovery
      Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
      Speaker: Tomasz Kostrzewski, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      3
      JAN 01, 2020 | 6:00 AM
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      3D-Micro Tissues in Translational Toxicology and Disease Modelling
      The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
      Speaker: Armin Wolf, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Microfabricated Human Liver Tissues for Drug Development
      Microfabricated Human Liver Tissues for Drug Development
      The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
      Speaker: Salman Khetani, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      OCT 10, 2019 | 10:30 AM
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Transcriptional Profiling of the Pediatric Tumor Microenvironment
      Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
      Speaker: Troy McEachron, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
    APR 29, 2020 | 6:00 AM
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    Looking for Evidence-Based Oncology? T̶r̶y̶ Do Targeted Proteomics!
    ...
    Speaker: Christian Regenbrecht, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 23, 2020 | 9:00 AM
    Keynote Presentation: Individualized Health
    Keynote Presentation: Individualized Health
    Learning Objectives: 1. What is wrong with healthcare today 2. What kinds of omics and wearables data can be used to best predict disease risk and manage health...
    Speaker: Michael Snyder, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 22, 2020 | 12:00 AM
    Clinical Applications of Estrogen Metabolism Genetic Testing: Improving Estrogen Health, Preventing Breast Cancer and Prescribing Estrogenic Medications with Precision
    Clinical Applications of Estrogen Metabolism Genetic Testing:...
    Estrogen metabolism is the ability to favorably excrete potentially toxic estrogens through urine and sweat. Impaired estrogen metabolism is associated with Endometriosis and Polycystic Ovar...
    Speaker: T.J. Hills
    Presented at: Genetics Week Virtual Event Series 2020
    3 1
     
     
  • APR 22, 2020 | 12:00 AM
    Priming the Precision Medicine Pipeline: New Models for Applied Genomics Education
    Priming the Precision Medicine Pipeline: New Models for Applied...
    As genomics plays an ever expanding role in healthcare and research, educational programs focused on applied genomics have not kept pace with the demand for trained students. In this talk, w...
    Speaker: Barbara Kraatz Fortini, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 22, 2020 | 12:00 AM
    Long-range technologies resolve complex genomic regions overlooked by short-read sequencing
    Long-range technologies resolve complex genomic regions overlooked...
    Complex genomes, including the human genome, contain ‘dark’ regions that standard short-read sequencing technologies do not adequately resolve—overlooking many variants tha...
    Speaker: Mark Ebbert, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 7:30 AM
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
    Novel CRISPR Knock-In Technology for the Robust Analysis of Cells...
    Modern biomedical research is being driven by large scale genetic and proteomic research to identify new targets for the study of disease mechanisms. While these techniques have been incredi...
    Speaker: Scott Soderling, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: CasTag Biosciences
    1 1
    APR 21, 2020 | 12:00 AM
    Single cell gene expression: new insights through the lens of full length mRNA isoform resolution
    Single cell gene expression: new insights through the lens of...
    Single cell RNA sequencing (scRNA-seq) emerged to characterize gene expression differences between individual cells, allowing a higher resolution look at mRNA abundance than bulk RNA- seq. H...
    Speaker: Jason Underwood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
     
     
  • APR 08, 2020 | 12:00 AM
    Collaborative Education for Talent of the Future
    Collaborative Education for Talent of the Future
    Strong performance for a Facility of the Future for the Life Sciences industry requires more than optimal manufacturing process development and facility design. The sector encompasses a dive...
    Speaker: Sue Behrens
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    The NISTmAb and Related Biopharmaceutical Resources
    The NISTmAb and Related Biopharmaceutical Resources
    The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
    Speaker: John Schiel, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
    There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
    Speaker: David Schaffer, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    2
    APR 02, 2020 | 8:00 AM
    Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
    Bionano Genome Imaging unravels complex structural rearrangements...
    DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
    Speaker: Eric Letouzé, PhD
    Sponsored By: Bionano
    14
    MAR 26, 2020 | 9:00 AM
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyond
    Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell...
    DATE: March 26, 2020 TIME: 9:00am PST, 12:00pm EST Growing demand for precision therapy and the recent successes with CAR-T cells for cancer treatment...
    Speaker: Namritha Ravinder
    Sponsored By: Thermo Fisher Scientific - Invitrogen
    7
     
     
  • MAR 11, 2020 | 10:30 AM
    Innate immunity in chronic neurodegeneration
    Innate immunity in chronic neurodegeneration
    The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
    Speaker: Michael Heneka, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    MAR 11, 2020 | 6:00 AM
    PANEL: The Neural Control of Locomotion, an Integrative Approach
    PANEL: The Neural Control of Locomotion, an Integrative Approach
    The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
    Speaker: Michael Dickinson, PhD , Anthony Azevedo, PhD , Clare Howard, PhD , Luke Brezovec , Sasha Rayshubskiy , Emily Palmer
    Presented at: Neuroscience Virtual Event Series 2020
    1
    FEB 25, 2020 | 10:00 AM
    Avances en la Tecnología del Diferencial de Glóbulos Blancos
    Avances en la Tecnología del Diferencial de Glóbulos Blancos
    DATE: 25 Febrero 2020 TIME: 13:00 COT, 10:00 PST Los desarrollos tecnológicos en analizadores automatizados de Hematología continúan transformando el laboratorio de Hema...
    Speaker: Don Wright
    Sponsored By: Abbott
    5 1
    JAN 01, 2020 | 6:00 AM
    Microphysiological Systems for Human Focused Drug Discovery
    Microphysiological Systems for Human Focused Drug Discovery
    Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
    Speaker: Tomasz Kostrzewski, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    3
    JAN 01, 2020 | 6:00 AM
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    3D-Micro Tissues in Translational Toxicology and Disease Modelling
    The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
    Speaker: Armin Wolf, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
     
     
  • JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Microfabricated Human Liver Tissues for Drug Development
    Microfabricated Human Liver Tissues for Drug Development
    The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
    Speaker: Salman Khetani, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    OCT 10, 2019 | 10:30 AM
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Transcriptional Profiling of the Pediatric Tumor Microenvironment
    Osteosarcoma (OS) is the most common bone tumor in pediatric and adolescent/young adult patients. Over the past three decades, significant improvements in the survival rates or therapeutic ap...
    Speaker: Troy McEachron, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
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