Neuroinflammation: inflammation of the nervous tissue. Thought to be initiated in response to a variety of cues: infection, traumatic brain injury, toxic metabolites, or autoimmunity.
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C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
Misfolded and accumulated neurodegenerative disease associated proteins (NDAPs, such as tau and alpha-synuclein) represent the major pathological hallmark in Alzheimer’s and Parkinson&...
DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
Several clinical and preclinical studies implicate abnormal endocannabinoid functioning and neuroinflammation as possible mechanisms in the pathophysiology of autism. Correcting these abnorma...