Natural sciences are concerned with the description, understanding and prediction of natural phenomena which are based on emperical evidence. Branches of natural sciences include physical sciences (chemistry, physics, astronomy) and life sciences (biology, zoology).
Current Status of Preimplantation Genetic Testing for Reciprocal Translocation Carriers in Koreans Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrange...
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
The fast spread of SARS-Cov-2 sparked much interest in understanding the underlying genomics of this 30,000bp Coronavirus. Thus far, thousands of genome assemblies are available, yet they fe...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
In his 2018 TED talk “How to build synthetic DNA and send it across the internet,” Dr. Dan Gibson highlighted a unique synthetic biology approach for fighting pandemics such as S...
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
Emerging infectious diseases” are those that are rapidly increasing in incidence or geographic range. Most are zoonotic, entering the human population from other animal species. None e...
Severe COVID-19 is characterized by dramatic immune system activation and inflammation. Several studies to modulate the immune response and limit immunopathology are ongoing. To better under...
With more than 6 million infections and more than 300,000 deaths (as of end of May 2020), the current COVID-19 pandemic has led to large scale lockdown around the world to prevent further sp...
While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
The mammary gland is a unique organ that develops predominantly after birth and undergoes dramatic remodelling in reproductive phases. Macrophages have been implicated in mammary gland funct...
DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
The central carbon metabolism including glycolysis, the pentose phosphate pathway, and the TCA-cycle is essential for all biological systems. The measurements of metabolites involved in thes...
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...
Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
Current Status of Preimplantation Genetic Testing for Reciprocal Translocation Carriers in Koreans Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrange...
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
The fast spread of SARS-Cov-2 sparked much interest in understanding the underlying genomics of this 30,000bp Coronavirus. Thus far, thousands of genome assemblies are available, yet they fe...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
In his 2018 TED talk “How to build synthetic DNA and send it across the internet,” Dr. Dan Gibson highlighted a unique synthetic biology approach for fighting pandemics such as S...
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
Emerging infectious diseases” are those that are rapidly increasing in incidence or geographic range. Most are zoonotic, entering the human population from other animal species. None e...
Severe COVID-19 is characterized by dramatic immune system activation and inflammation. Several studies to modulate the immune response and limit immunopathology are ongoing. To better under...
With more than 6 million infections and more than 300,000 deaths (as of end of May 2020), the current COVID-19 pandemic has led to large scale lockdown around the world to prevent further sp...
While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
The mammary gland is a unique organ that develops predominantly after birth and undergoes dramatic remodelling in reproductive phases. Macrophages have been implicated in mammary gland funct...
DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
The central carbon metabolism including glycolysis, the pentose phosphate pathway, and the TCA-cycle is essential for all biological systems. The measurements of metabolites involved in thes...
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...
Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
My laboratory at the Garvan Institute operates an ISO 15189 and NATA accredited laboratory for testing of patients using whole genome and whole exome sequencing, as well as gene panel testin...
The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
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