A monolayer is a single layer of atoms, molecules, or cells where each individual component is tightly packed to the next. The thickness of a monolayer equals the width of a single atom, molecule, or cell.
Most internal organs consist of a monolayer of polarized epithelial cells surrounding a central lumen that establish a barrier that segregates the internal medium from the outside environmen...
Date: April 26, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CET) Cell competition is a mechanism of interaction that dictates cell selection based on differences in cellular fitness. We...
Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
Date: April 20, 2021 Time: 10:00am (PST) In order to generate sufficient numbers of pluripotent stem cells (PSCs) for downstream applications, three-dimensional (3D) suspension cultures offe...
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
Deregulation of Receptor Tyrosine Kinase (RTK) signaling underlies a large fraction of human cancers. These genetic perturbations lead to a variety of cell autonomous and non-cell autonomous...
Madin Darby Canine Kidney (MDCK) cells can form a polarized epithelial layer in culture. We and others have observed that these layers are frequently characterized by extralayer cells, posit...
DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
Pancreatic β cell replacement therapy is considered as a potential strategy to treat diabetes. To date, transplantation of pancreatic islets from cadavers is the most effective approach...
When looking to answer complex biological questions, using in vitro techniques, you want the model that best reflects the in vivo condition. For decades two-dimensional cell culture has...
With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
Current methods for human induced pluripotent stem cells (hiPSC) derivation, expansion and differentiation can be limited in scalability and costly (due to their labor intensive nature). This...
DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA
In vitro translational models play a critical role in the drug discovery process because t...
The talk will first report on a new patented method of counting CTCs based on the metabolism of tumor cells, that favors acidification of their near environment. In order to maintain the acid...
DATE: September 20, 2016
TIME: 8:00am PST, 11:00 EST
Studies of cell-substrate interactions are important for an array of biotechnology applications. The nature of specific, recepto...
Most internal organs consist of a monolayer of polarized epithelial cells surrounding a central lumen that establish a barrier that segregates the internal medium from the outside environmen...
Date: April 26, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CET) Cell competition is a mechanism of interaction that dictates cell selection based on differences in cellular fitness. We...
Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
Date: April 20, 2021 Time: 10:00am (PST) In order to generate sufficient numbers of pluripotent stem cells (PSCs) for downstream applications, three-dimensional (3D) suspension cultures offe...
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
November 13, 2020 4:00 PM PST | November 14, 2020 8:00 AM SGT
Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
Three-dimensional (3D) cell culture spheroids and aggregates are preferred over monolayer cell culture due to their architectural and functional similarity to solid tumors. To study expressi...
Deregulation of Receptor Tyrosine Kinase (RTK) signaling underlies a large fraction of human cancers. These genetic perturbations lead to a variety of cell autonomous and non-cell autonomous...
Madin Darby Canine Kidney (MDCK) cells can form a polarized epithelial layer in culture. We and others have observed that these layers are frequently characterized by extralayer cells, posit...
DATE: September 24, 2019TIME: 7:00am PDTHigh throughput screening (HTS) is an effective method for identifying putative active compounds for therapeutics. Assays that evaluate changes i...
DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
Pancreatic β cell replacement therapy is considered as a potential strategy to treat diabetes. To date, transplantation of pancreatic islets from cadavers is the most effective approach...
When looking to answer complex biological questions, using in vitro techniques, you want the model that best reflects the in vivo condition. For decades two-dimensional cell culture has...
With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
Induced pluripotent stem (iPS) cells are a promising source of personalized therapy. These cells can provide immune-compatible autologous replacement tissue for the treatment of potentially a...
DATE: November 16, 2017TIME: 9:00AM PT, 12:00PM ETThe wide use of 2D monolayer cultures for cancer drug discovery reflects the technical ease of implementation for drug screening, and t...
Current methods for human induced pluripotent stem cells (hiPSC) derivation, expansion and differentiation can be limited in scalability and costly (due to their labor intensive nature). This...
DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
Cell Sciences Innovation, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ USA
In vitro translational models play a critical role in the drug discovery process because t...
The talk will first report on a new patented method of counting CTCs based on the metabolism of tumor cells, that favors acidification of their near environment. In order to maintain the acid...
DATE: September 20, 2016
TIME: 8:00am PST, 11:00 EST
Studies of cell-substrate interactions are important for an array of biotechnology applications. The nature of specific, recepto...
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