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Microsatellite Instability (MSI)
Often caused by mistakes that are left uncorrected when DNA has been copied in a cell, microsatellite instability (MSI) is a condition that occurs in a certain type of cell, such as a cancer cell, where regions of the repeated DNA alter in length, showing instability due to a defect in mismatch repair DNA proteins. Since the errors go uncorrected, they accumulate and through DNA replication, the sequences are not preserved, ultimately creating new microsatellites.
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OCT 23, 2023eBooksDownload your copy of "Enable precision medicine with comprehensive genomic profiling CGP" eBook to learn more ...SEP 19, 2022Genetics & Genomics
The promise of NGS in personalized cancer care For years, next-generation sequencing (NGS) has enabled oncologists to id ...Sponsored By: Roche SequencingAPR 09, 2020Cancer
Results from a study published in Nature Medicine highlights the benefits of receiving pre-surgery immunotherapy for som ...Written By: Kathryn DeMuth SullivanDEC 18, 2019Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.Written By: Carmen LeitchMAY 26, 2017Cancer
For the first time, the US FDA approved a cancer drug for patients based on presence of genetic biomarkers. Whereas canc ...
OCT 23, 2023
eBooks
Download your copy of "Enable precision medicine with comprehensive genomic profiling CGP" eBook to learn more
...
SEP 19, 2022
Genetics & Genomics
The promise of NGS in personalized cancer care For years, next-generation sequencing (NGS) has enabled oncologists to id
...
Sponsored By:
Roche Sequencing
APR 09, 2020
Cancer
Results from a study published in Nature Medicine highlights the benefits of receiving pre-surgery immunotherapy for som
...
Written By:
Kathryn DeMuth Sullivan
DEC 18, 2019
Genetics & Genomics
Cancer cells can adapt to mutations in the genome that might kill the cells by altering the activity of their genes.
Written By:
Carmen Leitch
MAY 26, 2017
Cancer
For the first time, the US FDA approved a cancer drug for patients based on presence of genetic biomarkers. Whereas canc
...