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Kynurenine
Kynurenine is a tryptophan metabolite generated by IDO-1 and TDO-2. Kynurenine binds to the ayrl hydrocarbon receptor (AHR) located on immune cells. Binding of kynurenine to AHR suppresses the immune response.
Kynurenine is a tryptophan metabolite generated by IDO-1 and TDO-2. Kynurenine binds to the ayrl hydrocarbon receptor (AHR) located on immune cells. Binding of kynurenine to AHR suppresses the immune response.
