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Interferon Gamma
Interferon gamma (IFN-γ) is a cytokine that facilitates innate and adaptive immune responses. IFN-γ is secreted by adaptive immune cells, including CD4+ T helper 1 (Th1) cells, CD8+ cytotoxic T cells (CTLs) and natural kills (NK) cells. Other cytokines regulate the expression of IFN-γ and its production can modulate cellular pathways including inflammation, cell proliferation, and cellular differentiation.
APR 20, 2021 | 4:30 PM
C.E. CREDITS
COVID-19 is a severe disease that has caused >1 million deaths in under one year. As this disease is novel, the molecular and cellular underpinnings of the progressive tissue injury are p...
MAR 25, 2021 | 11:00 AM
Date: March 25, 2021 Time: 11:00am (PDT) This is the second World TB Day and the end of the first full year since the world encountered COVID-19. We have all worked feverishly to manage this...
DEC 03, 2020 | 10:30 AM
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 20...
OCT 07, 2020 | 10:30 AM
Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
AUG 11, 2020 | 9:00 AM
DATE: August 11, 2020 TIME: 8:00am PDT The goal of TB elimination, less than 1 case per million people per year, can only be achieved through a concerted effort to detect and treat persons i...
JUN 03, 2020 | 12:00 AM
NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
MAY 20, 2020 | 1:15 PM
Background: Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematological malignancy. Despite recent advancements in the treatment of AML, approximately 50% of pat...
MAY 20, 2020 | 12:45 PM
Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
NOV 09, 2017 | 12:00 PM
QuantiFERON TB (QFT) was the first interferon gamma release assay (IGRA) utilizing whole blood stimulation as a test for TB infection, gaining FDA approval in 2001. Subsequently there have be...