Immuno-mediated diseases are characterized as conditions or disorders caused by abnormal immune cells. Immune cells work by identifying and eliminating foreign invaders in the body, such as cancer or infected cells. In cases where immune cells become overactive or mistakenly attack their own cells a variety of conditions can occur. Examples of immuno-mediated diseases include systemic lupus erythematous (SLE) and rheumatoid arthritis (RA), and type 1 diabetes.