Imaging: the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging.
In the battle between magnetism and superconductivity, magnetism wins so often that only a handful of magnetic superconductors are known. In this context, here we report our characterization...
Our work focuses on developing an optical brain-machine interface capable of interacting with neural activity in real-time. In this talk, I will describe our progress toward building the com...
Recent advances in super-resolution fluorescence microscopy based on single-molecule imaging have led to ~10 nm spatial resolution and exciting science. We are developing new approaches to a...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Carbon dioxide emissions, known to exacerbate climate change, have been increasing rapidly over the past century. One strategy to alleviate this issue is carbon capture and utilization (CCU)...
Allenes, compounds containing two double bonds across three contiguous carbons, are versatile synthetic intermediates due to their substituent loading capacity and ability to generate one or...
Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
DATE: July 30, 2020 TIME: 10:00am PT Regenerative medicine has become a key focus worldwide and the number of stem cell, especially pluripotent stem cell (PSC)-based clinical trials are rapi...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
July 29, 2020 TIME: 9:00am PDT, 12:009m EDT, 6:00pm CEST Hepatitis C infection, once a formidable enemy, is now a curable disease. Dramatic advances in antiviral therapies have launched a ne...
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
In this webinar, Dr. Luke O'Neill will discuss an overview of immunology and immunometabolism in infectious disease. The past 10 years or so has seen a major resurgence of interest in im...
In this webinar, Dr. Yuting Sun discusses her research supporting a Phase 1 clinical trial advancing cancer therapies, targeted at metabolic vulnerabilities. Metabolic rewiring is a hallmark...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
In the battle between magnetism and superconductivity, magnetism wins so often that only a handful of magnetic superconductors are known. In this context, here we report our characterization...
Our work focuses on developing an optical brain-machine interface capable of interacting with neural activity in real-time. In this talk, I will describe our progress toward building the com...
Recent advances in super-resolution fluorescence microscopy based on single-molecule imaging have led to ~10 nm spatial resolution and exciting science. We are developing new approaches to a...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
The Irvine CubeSat STEM Program (ICSP) is a collaboration between Irvine Public Schools Foundation, and Irvine and Tustin Unified school districts that provides teams of students from all si...
Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
Carbon dioxide emissions, known to exacerbate climate change, have been increasing rapidly over the past century. One strategy to alleviate this issue is carbon capture and utilization (CCU)...
Allenes, compounds containing two double bonds across three contiguous carbons, are versatile synthetic intermediates due to their substituent loading capacity and ability to generate one or...
Protein structural disorder helps avoid misfolding and aggregation, but in impeding protein folding might also impede function. The balance between these two selective pressures on protein b...
DATE: July 30, 2020 TIME: 10:00am PT Regenerative medicine has become a key focus worldwide and the number of stem cell, especially pluripotent stem cell (PSC)-based clinical trials are rapi...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
July 29, 2020 TIME: 9:00am PDT, 12:009m EDT, 6:00pm CEST Hepatitis C infection, once a formidable enemy, is now a curable disease. Dramatic advances in antiviral therapies have launched a ne...
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
In this webinar, Dr. Luke O'Neill will discuss an overview of immunology and immunometabolism in infectious disease. The past 10 years or so has seen a major resurgence of interest in im...
In this webinar, Dr. Yuting Sun discusses her research supporting a Phase 1 clinical trial advancing cancer therapies, targeted at metabolic vulnerabilities. Metabolic rewiring is a hallmark...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...