Gene mapping plots the locations of genes on chromosomes, and they can be used to predict genes which are inherited together. The closer genes are located to one another on a chromosome increases the probability of being inherited together.
Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
Cellular processes are orchestrated by a large number of biomolecules in a spatially and temporally coordinated manner within a tiny volume. To uncover the underlying organizational principle...
In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
Nucleotide variation in gene regulatory elements is a major cause of human disease. Despite continual progress in the cataloging of these elements, little is known about the code and grammati...
Characterizing cellular hierarchy has profound implications in development and diseases. Single-cell technologies have great potential in discovering new cell types and lineage relationships,...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
DATE: November 8, 2016
TIME: 10:00am PT, 1:00pm ET
Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing
We have assemble...
DATE: October 19, 2016
TIME: 9:00 AM PT, 12:00 PM ET, 6:00 PM CEST
Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
DATE: June 22, 2016
TIME: 9am Pacific time, 12pm Eastern time, 6pm Central European time
A large fraction of the RNA transcribed in eukaryotic cells is rapidly degraded in the nucleus. A ...
The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
10:00AM PT, 12:00PM CT, 1:00PM ET
RNA sequencing (RNA-seq) has revolutionized the study of gene expression in animals, plants and microorganisms. However, because of its high cost, this te...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
Cellular processes are orchestrated by a large number of biomolecules in a spatially and temporally coordinated manner within a tiny volume. To uncover the underlying organizational principle...
In the US, the National Antimicrobial Resistance Monitoring System has been using WGS of Salmonella as a tool of routine surveillance since 2013. To date, NARMS has generated MIC and WGS data...
Our understanding of how genotype controls phenotype is limited by the scale at which we can precisely alter the genome and assess the phenotypic consequences of each perturbation. In this pr...
In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
DATE: June 28, 2017TIME: 9:00AM PDT, 12:00PM EDT, 6:00PM CESTMany RNA binding proteins (RBPs) regulate the selection of alternative polyA sites. To understand their regulatory principle...
Nucleotide variation in gene regulatory elements is a major cause of human disease. Despite continual progress in the cataloging of these elements, little is known about the code and grammati...
Characterizing cellular hierarchy has profound implications in development and diseases. Single-cell technologies have great potential in discovering new cell types and lineage relationships,...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
DATE: November 8, 2016
TIME: 10:00am PT, 1:00pm ET
Stock and individual identification of Coho and Chinook Salmon in British Columbia via amplicon sequencing
We have assemble...
DATE: October 19, 2016
TIME: 9:00 AM PT, 12:00 PM ET, 6:00 PM CEST
Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without ...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and va...
DATE: June 22, 2016
TIME: 9am Pacific time, 12pm Eastern time, 6pm Central European time
A large fraction of the RNA transcribed in eukaryotic cells is rapidly degraded in the nucleus. A ...
The biological state of the cell is characterized by a complex network of interacting genes, gene products, proteins, microRNAs, as well as other molecules. Microarrays and next generation se...
10:00AM PT, 12:00PM CT, 1:00PM ET
RNA sequencing (RNA-seq) has revolutionized the study of gene expression in animals, plants and microorganisms. However, because of its high cost, this te...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
Understanding systematic biases in primary research are important for appropriate interpretation of research and recognizing features of reproducible research. Systematic biases arise from th...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
Perhaps the greatest surprise of genetic studies of human disease is that 90% of top-scoring disease-associated loci lie outside protein-coding regions. This has increased the urgency of mapp...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
The ENCODE and modENCODE consortia have generated a resource containing large amounts of transcriptomic data, extensive mapping of chromatin states, as well as the binding locations of >30...
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