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    Drug Design

    Drug Design: often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.

    Webinars

    • APR 29, 2020 | 6:00 AM
      Multiplexed Detection and Characterization of Anti-Drug Antibody Responses in Humans
      Multiplexed Detection and Characterization of Anti-Drug Antibody...
      ...
      Speaker: Paul Rhyne, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Nanotherapeutics: An insight into healthcare and future multi-dimensional clinical applications
      Nanotherapeutics: An insight into healthcare and future multi-dimensional...
      In recent years Nanotherapeutics has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. It involves design, fabrication, r...
      Speaker: Pratibha Kakadia, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      Hybrid Modeling and Intensified DoE Enabling Faster Process Development, Soft Sensors and Model Predictive Control
      Hybrid Modeling and Intensified DoE Enabling Faster Process Development,...
      Within this talk the advantages of using intensified Design of experiments (iDoE) in combination with hybrid modeling will be demonstrated. In detailed upstream and downstream showcases the...
      Speaker: Mark Dürkop, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1 1
      APR 03, 2020 | 9:00 AM
      BioGX SARS-Cov-2 Reagents for BD MAX™ System Webinar
      BioGX SARS-Cov-2 Reagents for BD MAX™ System Webinar
      DATE: April 3, 2020 TIME: 9:00am PT, 12:00pm ET The BioGX SARS-CoV-2 Reagents for BD MAX™ System is a real-time RT-PCR test intended for the qualitative detection of nucleic acid from...
      Speaker: Nikos Pavlidis , Dr. Patrick Murray, Ph.D. , Celine Roger-Dalbert , Diane Kawa, PhD
      Sponsored By: BD
      5
      MAR 25, 2020 | 12:00 AM
      Cannabis 101 for the Healthcare Professional: What you need to know to answer your patients' questions and feel good about it!
      Cannabis 101 for the Healthcare Professional: What you need to...
      Healthcare providers are increasingly being asked from their patients for advice and recommendations for the use of cannabis in all types of conditions and disease states. One of the most ch...
      Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP
      Presented at: Cannabis Sciences Virtual Event Series 2020
      2
      MAR 25, 2020 | 12:00 AM
      Solving the Hemp Challenge: Pesticide Detection
      Solving the Hemp Challenge: Pesticide Detection
      With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
      Speaker: Avinash Dalmia, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2020
      1
      FEB 26, 2020 | 7:30 AM
      Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
      Keynote Presentation: Emerging Drug Combinations: Evolution From...
      Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      FEB 25, 2020 | 9:00 AM
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 1
      JAN 23, 2020 | 9:00 AM
      A Workflow for Knock-in Genome Editing: Simplified
      A Workflow for Knock-in Genome Editing: Simplified
      DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
      Speaker: Matthew Poling, PhD
      Sponsored By: Thermo Fisher Scientific - Invitrogen
      17
      JAN 01, 2020 | 6:00 AM
      Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
      Using 3D cell culture models and high content confocal imaging...
      With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
      Speaker: Erin Edwards, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Microfabricated Human Liver Tissues for Drug Development
      Microfabricated Human Liver Tissues for Drug Development
      The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
      Speaker: Salman Khetani, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Organoids: A Revolutionary New Tool for Drug Screening
      Organoids: A Revolutionary New Tool for Drug Screening
      “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
      Speaker: Rekha Pal, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Selective D4R Ligands Reveal Structure-Activity Relationships that Engender Agonist Efficacy
      Selective D4R Ligands Reveal Structure-Activity Relationships...
      The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
      Speaker: Comfort Boateng, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      NOV 06, 2019 | 10:30 AM
      Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses
      Drug discovery and pharmacology of antivirals targeting drug-resistant...
      The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
      Speaker: Jun Wang, PhD
      Presented at: Influenza Virtual Event Series 2019
      6
      OCT 24, 2019 | 10:30 AM
      Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
      Supercritical fluid chromatography of polar biomolecules at the...
      Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
      Speaker: Raffeal Bennett, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      OCT 22, 2019 | 9:00 AM
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
      DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
      Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
      Sponsored By: Advanced Instruments
      10 1
      OCT 03, 2019 | 12:00 PM
      Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
      Gene Editing Success: Considerations for maximizing your CRISPR...
      CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
      Speaker: Ryan Donnelly
      Presented at: CRISPR Virtual Event Series 2019
      Sponsored By: Horizon Discovery
      2
      OCT 03, 2019 | 6:00 AM
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      CRISPR Regulations: Rewriting DNA and Rethinking GMOs
      First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
      Speaker: Lea Witkowsky, PhD
      Presented at: CRISPR Virtual Event Series 2019
      5
      OCT 01, 2019 | 8:00 AM
      Looking under the Hood and Getting Started with the Optima AUC
      Looking under the Hood and Getting Started with the Optima AUC
      DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
      Speaker: Akash Bhattacharya, PhD , Ross VerHeul
      Sponsored By: Beckman Coulter Life Sciences
      4
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      SEP 12, 2019 | 10:30 AM
      Analysis of human gut microbiomes and antibiotic resistomes of pediatric patients undergoing stem cell transplantation
      Analysis of human gut microbiomes and antibiotic resistomes of...
      The emergence and spread of antimicrobial-resistant (AMR) bacteria and resistance mechanisms pose a serious challenge to laboratories in both hospital clinical microbiology and public health...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: QIAGEN
      5
      SEP 11, 2019 | 1:30 PM
      Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
      Development of Machine Learning Algorithms to Data Mine Meta-Omic...
      Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: PacBio
      4
      SEP 10, 2019 | 9:00 AM
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
      Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
      DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
      Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
      Sponsored By: Beckman Coulter Life Sciences
      13
    APR 29, 2020 | 6:00 AM
    Multiplexed Detection and Characterization of Anti-Drug Antibody Responses in Humans
    Multiplexed Detection and Characterization of Anti-Drug Antibody...
    ...
    Speaker: Paul Rhyne, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 22, 2020 | 12:00 AM
    Nanotherapeutics: An insight into healthcare and future multi-dimensional clinical applications
    Nanotherapeutics: An insight into healthcare and future multi-dimensional...
    In recent years Nanotherapeutics has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. It involves design, fabrication, r...
    Speaker: Pratibha Kakadia, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    Hybrid Modeling and Intensified DoE Enabling Faster Process Development, Soft Sensors and Model Predictive Control
    Hybrid Modeling and Intensified DoE Enabling Faster Process Development,...
    Within this talk the advantages of using intensified Design of experiments (iDoE) in combination with hybrid modeling will be demonstrated. In detailed upstream and downstream showcases the...
    Speaker: Mark Dürkop, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1 1
    APR 03, 2020 | 9:00 AM
    BioGX SARS-Cov-2 Reagents for BD MAX™ System Webinar
    BioGX SARS-Cov-2 Reagents for BD MAX™ System Webinar
    DATE: April 3, 2020 TIME: 9:00am PT, 12:00pm ET The BioGX SARS-CoV-2 Reagents for BD MAX™ System is a real-time RT-PCR test intended for the qualitative detection of nucleic acid from...
    Speaker: Nikos Pavlidis , Dr. Patrick Murray, Ph.D. , Celine Roger-Dalbert , Diane Kawa, PhD
    Sponsored By: BD
    5
     
     
  • MAR 25, 2020 | 12:00 AM
    Cannabis 101 for the Healthcare Professional: What you need to know to answer your patients' questions and feel good about it!
    Cannabis 101 for the Healthcare Professional: What you need to...
    Healthcare providers are increasingly being asked from their patients for advice and recommendations for the use of cannabis in all types of conditions and disease states. One of the most ch...
    Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP
    Presented at: Cannabis Sciences Virtual Event Series 2020
    2
    MAR 25, 2020 | 12:00 AM
    Solving the Hemp Challenge: Pesticide Detection
    Solving the Hemp Challenge: Pesticide Detection
    With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
    Speaker: Avinash Dalmia, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2020
    1
    FEB 26, 2020 | 7:30 AM
    Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
    Keynote Presentation: Emerging Drug Combinations: Evolution From...
    Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    FEB 25, 2020 | 9:00 AM
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 1
    JAN 23, 2020 | 9:00 AM
    A Workflow for Knock-in Genome Editing: Simplified
    A Workflow for Knock-in Genome Editing: Simplified
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Speaker: Matthew Poling, PhD
    Sponsored By: Thermo Fisher Scientific - Invitrogen
    17
     
     
  • JAN 01, 2020 | 6:00 AM
    Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
    Using 3D cell culture models and high content confocal imaging...
    With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
    Speaker: Erin Edwards, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Microfabricated Human Liver Tissues for Drug Development
    Microfabricated Human Liver Tissues for Drug Development
    The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
    Speaker: Salman Khetani, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Organoids: A Revolutionary New Tool for Drug Screening
    Organoids: A Revolutionary New Tool for Drug Screening
    “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
    Speaker: Rekha Pal, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Selective D4R Ligands Reveal Structure-Activity Relationships that Engender Agonist Efficacy
    Selective D4R Ligands Reveal Structure-Activity Relationships...
    The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
    Speaker: Comfort Boateng, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    NOV 06, 2019 | 10:30 AM
    Drug discovery and pharmacology of antivirals targeting drug-resistant influenza viruses
    Drug discovery and pharmacology of antivirals targeting drug-resistant...
    The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
    Speaker: Jun Wang, PhD
    Presented at: Influenza Virtual Event Series 2019
    6
     
     
  • OCT 24, 2019 | 10:30 AM
    Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
    Supercritical fluid chromatography of polar biomolecules at the...
    Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
    Speaker: Raffeal Bennett, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    OCT 22, 2019 | 9:00 AM
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
    DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
    Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
    Sponsored By: Advanced Instruments
    10 1
    OCT 03, 2019 | 12:00 PM
    Gene Editing Success: Considerations for maximizing your CRISPR gene editing accuracy and efficiency
    Gene Editing Success: Considerations for maximizing your CRISPR...
    CRISPR based gene editing has proven to be an incredibly powerful tool for studying functions of individual proteins, understanding the role of multi-gene pathways, and even knocking out prot...
    Speaker: Ryan Donnelly
    Presented at: CRISPR Virtual Event Series 2019
    Sponsored By: Horizon Discovery
    2
    OCT 03, 2019 | 6:00 AM
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    CRISPR Regulations: Rewriting DNA and Rethinking GMOs
    First discovered as a genome-editing tool just seven years ago, CRISPR systems have already changed the face of basic research, allowing researchers to alter the DNA of hundreds of organisms...
    Speaker: Lea Witkowsky, PhD
    Presented at: CRISPR Virtual Event Series 2019
    5
    OCT 01, 2019 | 8:00 AM
    Looking under the Hood and Getting Started with the Optima AUC
    Looking under the Hood and Getting Started with the Optima AUC
    DATE: October 1, 2019TIME: 8:00am PTIn the webinar, Introduction to Characterization of Biomolecules Using Analytical Ultracentrifugation, we discussed the fundamentals of analytical...
    Speaker: Akash Bhattacharya, PhD , Ross VerHeul
    Sponsored By: Beckman Coulter Life Sciences
    4
     
     
  • SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    SEP 12, 2019 | 10:30 AM
    Analysis of human gut microbiomes and antibiotic resistomes of pediatric patients undergoing stem cell transplantation
    Analysis of human gut microbiomes and antibiotic resistomes of...
    The emergence and spread of antimicrobial-resistant (AMR) bacteria and resistance mechanisms pose a serious challenge to laboratories in both hospital clinical microbiology and public health...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: QIAGEN
    5
    SEP 11, 2019 | 1:30 PM
    Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
    Development of Machine Learning Algorithms to Data Mine Meta-Omic...
    Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: PacBio
    4
    SEP 10, 2019 | 9:00 AM
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit for selecting antibodies with the complete panel in mind
    Not Your Typical Flow Cytometry Panel Design Webinar: A tool kit...
    DATE: September 10, 2019TIME: 9:00am PDTAfter new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next topic to ma...
    Speaker: Maria Gentile, MSc , Michael Kapinsky, PhD
    Sponsored By: Beckman Coulter Life Sciences
    13
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