Follow
Drug Design
Drug Design: often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target.
-
AUG 07, 2020 | 10:30 AM
In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...AUG 06, 2020 | 10:00 AM
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...AUG 06, 2020 | 10:00 AM
DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...JUL 29, 2020 | 4:00 PM
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...JUL 29, 2020 | 12:00 AM
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...JUN 30, 2020 | 9:00 AM
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...JUN 23, 2020 | 9:00 AM
DATE: June 23, 2020 TIME: 9:00am PDT I n the last eight years the field of Synthetic Biology has erupted into a massive industry driving innovation in multiple disciplines, from sustainable...JUN 17, 2020 | 12:00 PM
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...Speaker: Susan Zolla-Pazner, PhDJUN 17, 2020 | 10:00 AM
...Speaker: Sushmita (Mimi) Roy, PhD , Rahul Raman, PhDPresented at: Agilent's Virtual Mass Spectacular!
JUN 03, 2020 | 12:00 PM
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...Speaker: Pratip K. ChattopadhyayJUN 02, 2020 | 9:00 AM
DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...MAY 20, 2020 | 7:30 AM
Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...MAY 20, 2020 | 12:00 AM
Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...Speaker: Mark Kiel, MD, PhDMAY 20, 2020 | 12:00 AM
We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...Speaker: Luke Ghislain, PhDMAY 14, 2020 | 11:00 AM
Concerns about the quality of published animal research include inefficient or flawed study design, inappropriate statistical analysis and incomplete reporting. The ARRIVE guidelines were de...Speaker: Nathalie Percie du Sert, PhDPresented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 14, 2020 | 9:00 AM
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...Speaker: Joseph Garner, PhD , Brianna Gaskill, PhDPresented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 14, 2020 | 7:30 AM
Inherent in research, is the simplification of a complex world into a testing space to explore cause and effect. Across preclinical research, questions are being raised on the testing space...MAY 14, 2020 | 6:00 AM
In the course of the so-called reproducibility crisis, various sources of poor reproducibility of animal research have been identified, including a lack of scientific rigor, low statistical...MAY 14, 2020 | 12:00 AM
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...Speaker: Jamie Ahloy Dallaire, MSc, PhDPresented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 12, 2020 | 9:00 AM
NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...MAY 07, 2020 | 8:00 AM
DATE: May 7, 2020 TIME: 8:00AM PDT, 11:00AM EDT With the recent explosion of cell therapy, we know more about conditions affecting cell growth than ever before. Your CO2 incubator should not...MAY 07, 2020 | 7:00 AM
DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...MAY 06, 2020 | 12:00 AM
The potential for cognitive bias in forensic evidence interpretation and crime scene investigation continues to receive attention and debate within forensic and academic communities. Startin...APR 29, 2020 | 6:00 AM
...
AUG 07, 2020 | 10:30 AM
In this presentation, I will discuss my experiences leading to my current position as a scientist and team leader, focused on chemical biology and drug discovery in the pharmaceutical indust...
AUG 06, 2020 | 10:00 AM
One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
AUG 06, 2020 | 10:00 AM
DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
JUL 29, 2020 | 4:00 PM
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
JUL 29, 2020 | 12:00 AM
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
JUN 30, 2020 | 9:00 AM
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
JUN 23, 2020 | 9:00 AM
DATE: June 23, 2020 TIME: 9:00am PDT I n the last eight years the field of Synthetic Biology has erupted into a massive industry driving innovation in multiple disciplines, from sustainable...
JUN 17, 2020 | 12:00 PM
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
Speaker:
Susan Zolla-Pazner, PhD
JUN 17, 2020 | 10:00 AM
...
Speaker:
Sushmita (Mimi) Roy, PhD
, Rahul Raman, PhD
Presented at: Agilent's Virtual Mass Spectacular!
JUN 03, 2020 | 12:00 PM
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
Speaker:
Pratip K. Chattopadhyay
JUN 02, 2020 | 9:00 AM
DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
MAY 20, 2020 | 7:30 AM
Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
MAY 20, 2020 | 12:00 AM
Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
Speaker:
Mark Kiel, MD, PhD
MAY 20, 2020 | 12:00 AM
We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...
Speaker:
Luke Ghislain, PhD
MAY 14, 2020 | 11:00 AM
Concerns about the quality of published animal research include inefficient or flawed study design, inappropriate statistical analysis and incomplete reporting. The ARRIVE guidelines were de...
Speaker:
Nathalie Percie du Sert, PhD
Presented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 14, 2020 | 9:00 AM
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...
Speaker:
Joseph Garner, PhD
, Brianna Gaskill, PhD
Presented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 14, 2020 | 7:30 AM
Inherent in research, is the simplification of a complex world into a testing space to explore cause and effect. Across preclinical research, questions are being raised on the testing space...
MAY 14, 2020 | 6:00 AM
In the course of the so-called reproducibility crisis, various sources of poor reproducibility of animal research have been identified, including a lack of scientific rigor, low statistical...
MAY 14, 2020 | 12:00 AM
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Speaker:
Jamie Ahloy Dallaire, MSc, PhD
Presented at: Laboratory Animal Sciences Virtual Event Series 2020
MAY 12, 2020 | 9:00 AM
NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
MAY 07, 2020 | 8:00 AM
DATE: May 7, 2020 TIME: 8:00AM PDT, 11:00AM EDT With the recent explosion of cell therapy, we know more about conditions affecting cell growth than ever before. Your CO2 incubator should not...
MAY 07, 2020 | 7:00 AM
DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
MAY 06, 2020 | 12:00 AM
The potential for cognitive bias in forensic evidence interpretation and crime scene investigation continues to receive attention and debate within forensic and academic communities. Startin...
APR 29, 2020 | 6:00 AM
...