Developmental Biology: the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction and metamorphosis and the growth and differentiation of stem cells in the adult organism.
Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
MicroRNAs (miRs) are small non-coding RNAs whose expression is altered in several types of human cancers. Recent evidence supports their inter-cellular transfer through extracellular vesicle...
Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
Learning Objectives: 1. Understand methods of isolating and enriching exosomes along with their pros/cons of the different techniques 2. What do we mean when we talk about subtyping, and wha...
The extracellular matrix (ECM) is a three-dimensional structure that provides physical support for tissues/organs and biochemical/biomechanical cues for tissue morphogenesis, differentiation...
GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
Reactive oxygen species (ROS) are well-known for their detrimental effects leading to oxidative stress, cell death, aging, and degenerative disorders. However, there is increasing evidence t...
The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
My group is addressing fundamental questions in evolutionary biology, using both genome- and phenotype-first approaches. A few years ago, we discovered that Arabidopsis thaliana is a great m...
Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
Why do some individuals live longer than others? Even identical twins have different lifespans, as do genetically identical model organisms raised in controlled laboratory environments. What...
DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
DATE: July 21, 2020 TIME: 8:00am PDT, 11:00am EDT The adult brain is composed of densely interwoven neuronal and vascular networks that are essential for proper function. Understanding the s...
Current Status of Preimplantation Genetic Testing for Reciprocal Translocation Carriers in Koreans Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrange...
DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
Almost unidimensional in their primordial existence as single cells, multicellular organisms quickly develop into complex 3D architectures and machineries composed of multiple cells and tiss...
During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation....
Although much is known about the molecular maternal-fetal interactions during implantation, the 3D architecture of the uterine environment in which the early embryo develops is not well unde...
How organisms control organ size is a fundamental question in developmental and regenerative biology. The underlaying mechanisms are not well defined. For instance, we don’t fully unde...
Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
MicroRNAs (miRs) are small non-coding RNAs whose expression is altered in several types of human cancers. Recent evidence supports their inter-cellular transfer through extracellular vesicle...
Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
Learning Objectives: 1. Understand methods of isolating and enriching exosomes along with their pros/cons of the different techniques 2. What do we mean when we talk about subtyping, and wha...
The extracellular matrix (ECM) is a three-dimensional structure that provides physical support for tissues/organs and biochemical/biomechanical cues for tissue morphogenesis, differentiation...
GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
I will present our new computer vision algorithm, ST-Net, which can computationally synthesize spatially resolved transcriptomics directly from H&E histology images (He et al. Nature Bio...
Reactive oxygen species (ROS) are well-known for their detrimental effects leading to oxidative stress, cell death, aging, and degenerative disorders. However, there is increasing evidence t...
The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
My group is addressing fundamental questions in evolutionary biology, using both genome- and phenotype-first approaches. A few years ago, we discovered that Arabidopsis thaliana is a great m...
Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
DATE: September 3, 2020 TIME: 9:00 am PDT, 12:00 pm EDT So many considerations go into a lab. How many fume hoods do I need? What chemicals can they handle and how often? What about ducting?...
Over 100 distinct alkane monooxygenase (AlkB) enzymes containing a covalently bound, or fused, rubredoxin domain were identified and analyzed using bioinformatic techniques. One such protein...
Why do some individuals live longer than others? Even identical twins have different lifespans, as do genetically identical model organisms raised in controlled laboratory environments. What...
DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
DATE: July 21, 2020 TIME: 8:00am PDT, 11:00am EDT The adult brain is composed of densely interwoven neuronal and vascular networks that are essential for proper function. Understanding the s...
Current Status of Preimplantation Genetic Testing for Reciprocal Translocation Carriers in Koreans Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrange...
DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
Almost unidimensional in their primordial existence as single cells, multicellular organisms quickly develop into complex 3D architectures and machineries composed of multiple cells and tiss...
During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation....
Although much is known about the molecular maternal-fetal interactions during implantation, the 3D architecture of the uterine environment in which the early embryo develops is not well unde...
How organisms control organ size is a fundamental question in developmental and regenerative biology. The underlaying mechanisms are not well defined. For instance, we don’t fully unde...
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