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    Clinical Research

    Clinical Research: Patient - oriented research. Clinical research is a branch of healthcare science that determines the safety and effectiveness (efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease.

    Webinars

    • OCT 30, 2014 | 10:30 AM
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool for Optimizing Drug Management
      Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool...
      Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
      Speaker: William Clarke, PhD, MBA, DABCC
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 30, 2014 | 10:30 AM
      Development of molecularly targeted imaging agents and identification of novel targets in cancer
      Development of molecularly targeted imaging agents and identification...
      The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
      Speaker: Kimberly Kelly , PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 10:30 AM
      Genomics in the Clinic: Promises and Challenges
      Genomics in the Clinic: Promises and Challenges
      Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
      Speaker: John Carpten, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 9:00 AM
      Parathyroidism: Hypo, Hyper....what is normal, really?
      Parathyroidism: Hypo, Hyper....what is normal, really?
       Hyper and Hypoparathyroid disease states are often latent with a multiplicity of manifestations ranging from asymptomatic state to obvious symptoms and complications such as fatigue...
      Speaker: D Sudhaker Rao, MB,BS, FACP, FACE
      Presented at: Discover More; Your Virtual Resource
      Sponsored By: Diasorin
      26
      OCT 30, 2014 | 9:00 AM
      A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
      A head-to-head comparison of whole blood derived samples (cfDNA...
      Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
      Speaker: Paul W. Dempsey, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 30, 2014 | 6:00 AM
      A platform for combining the results of WES and RNA-seq analysis
      A platform for combining the results of WES and RNA-seq analysis
      Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
      Speaker: Naomi Thomson
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 30, 2014 | 6:00 AM
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
      Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
      When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 3:00 PM
      Transforming the future of oncology with genomics
      Transforming the future of oncology with genomics
      Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
      Speaker: Jennifer Stone, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      13
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 3:00 PM
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
      Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
      Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
      Speaker: Peter Blume-Jensen, MD, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      0
      OCT 29, 2014 | 1:30 PM
      Metabolic therapy for the adjuvant treatment of malignant brain tumors
      Metabolic therapy for the adjuvant treatment of malignant brain...
      Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
      Speaker: Adrienne C. Scheck, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 29, 2014 | 12:00 PM
      A Next-Gen Sequencing Software Workflow for Cancer Gene Panel Analysis
      A Next-Gen Sequencing Software Workflow for Cancer Gene Panel...
      DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. The software supports a variety of key workflows...
      Speaker: Kerri Phillips
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      8
      OCT 29, 2014 | 9:00 AM
      What's wrong with biomarker development for cancer
      What's wrong with biomarker development for cancer
      Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
      Speaker: Anna Barker, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      OCT 29, 2014 | 9:00 AM
      Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
      Reading and disrupting the histone code with chemical agents:...
      Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
      Speaker: Fraser Hof, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      7
      OCT 29, 2014 | 7:30 AM
      Making Clinical NGS possible
      Making Clinical NGS possible
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
      OCT 29, 2014 | 7:30 AM
      Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
      Targeting the oncogene eIF4E in leukemia reveals a new form of...
      The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
      Speaker: Katherine LB Borden, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      40
      OCT 29, 2014 | 7:30 AM
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
      Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
      Speaker: Darran O'Connor, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      OCT 24, 2014 | 12:00 PM
      What to Do About Flu in 2014
      What to Do About Flu in 2014
        Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
      Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
      Sponsored By: Alere, Alere
      36
      OCT 14, 2014 | 1:00 AM
      Aggregation Analysis and Beyond: Analytical Ultracentrifugation in the Biopharmaceutical Industry
      Aggregation Analysis and Beyond: Analytical Ultracentrifugation...
        AUC sedimentation velocity (SV) has a longstanding reputation as being the gold standard for the matrix free quantification of aggregates in biopharmaceuticals. The continuous c(S) ...
      Speaker: Alexander Bepperling, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      30
      SEP 25, 2014 | 8:00 AM
      Grow your LC-MS research and forensic lab profitability with cost-effective analytical workflows
      Grow your LC-MS research and forensic lab profitability with cost-effective...
        This webinar presents LC-MS workflows for cost-effective research and forensic laboratory operation. The workflows, enabled by simple sample preparation coupled with rapid analysis ...
      Speaker: Joseph Di Bussolo, PhD
      Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
      16
      SEP 24, 2014 | 3:00 PM
      Site-directed ligand discovery for cryptic sites and other challenging targets
      Site-directed ligand discovery for cryptic sites and other challenging...
      Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
      Speaker: Michelle Arkin, PhD
      Presented at: Advances in Drug Discovery and Development
      20
      SEP 24, 2014 | 2:00 PM
      Targeting Lysine Acetylation in Cancer
      Targeting Lysine Acetylation in Cancer
      Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
      Speaker: Jay Bradner, MD
      Presented at: Advances in Drug Discovery and Development
      18
      SEP 24, 2014 | 1:00 PM
      The VCNDD: CNS Drug Discovery in Academia
      The VCNDD: CNS Drug Discovery in Academia
      This lecture will provide an overview of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD), focusing on how an Academic Drug Discovery Center was established and is maintained. I...
      Speaker: Craig W. Lindsley, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      6
      SEP 24, 2014 | 12:00 PM
      The Accurate Prediction of Ligand Binding Free Energies
      The Accurate Prediction of Ligand Binding Free Energies
      In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
      Speaker: Mark Murcko, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      22
    OCT 30, 2014 | 10:30 AM
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool for Optimizing Drug Management
    Therapeutic Drug Monitoring (TDM) in Cancer Chemotherapy: A Tool...
    Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
    Speaker: William Clarke, PhD, MBA, DABCC
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 30, 2014 | 10:30 AM
    Development of molecularly targeted imaging agents and identification of novel targets in cancer
    Development of molecularly targeted imaging agents and identification...
    The era of omics has ushered in the hope for personalized medicine. Proteomic and genomic strategies that allow unbiased identification of genes and proteins and their post-transcriptional a...
    Speaker: Kimberly Kelly , PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 10:30 AM
    Genomics in the Clinic: Promises and Challenges
    Genomics in the Clinic: Promises and Challenges
    Uncovering the genetic lesions underpinning cancer through genomic profiling in a clinical setting could provide insights into possible treatment options for oncologists and their patients. N...
    Speaker: John Carpten, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 9:00 AM
    Parathyroidism: Hypo, Hyper....what is normal, really?
    Parathyroidism: Hypo, Hyper....what is normal, really?
     Hyper and Hypoparathyroid disease states are often latent with a multiplicity of manifestations ranging from asymptomatic state to obvious symptoms and complications such as fatigue...
    Speaker: D Sudhaker Rao, MB,BS, FACP, FACE
    Presented at: Discover More; Your Virtual Resource
    Sponsored By: Diasorin
    26
    OCT 30, 2014 | 9:00 AM
    A head-to-head comparison of whole blood derived samples (cfDNA vs CTC DNA) for cancer research using next-generation sequencing
    A head-to-head comparison of whole blood derived samples (cfDNA...
    Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
    Speaker: Paul W. Dempsey, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 30, 2014 | 6:00 AM
    A platform for combining the results of WES and RNA-seq analysis
    A platform for combining the results of WES and RNA-seq analysis
    Cancer research is being revolutionized by targeted gene panels, whole exome sequencing (WES), whole genome sequencing (WGS), and transcriptome sequencing (RNA-Seq).Many analyses, such as...
    Speaker: Naomi Thomson
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
    OCT 30, 2014 | 6:00 AM
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative Neoplasms
    Epigenetic Dysregulation in the Pathogenesis of Myeloproliferative...
    When the BCR/ABL1 fusion protein was identified in chronic myelogenous leukemia and the JAK2 V617F mutation was identified in patients with other myeloproliferative neoplasms (MPNs) such as p...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
    OCT 29, 2014 | 3:00 PM
    Transforming the future of oncology with genomics
    Transforming the future of oncology with genomics
    Illumina next-generation sequencing (NGS) and microarray technologies are revolutionizing cancer research, enabling cancer variant discovery and detection and molecular monitoring. Join u...
    Speaker: Jennifer Stone, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    13
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 3:00 PM
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches for proper patient selection
    Drug-tailored, efficacy-predictive and prognostic biomarker approaches...
    Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
    Speaker: Peter Blume-Jensen, MD, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    0
     
     
  • OCT 29, 2014 | 1:30 PM
    Metabolic therapy for the adjuvant treatment of malignant brain tumors
    Metabolic therapy for the adjuvant treatment of malignant brain...
    Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
    Speaker: Adrienne C. Scheck, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 29, 2014 | 12:00 PM
    A Next-Gen Sequencing Software Workflow for Cancer Gene Panel Analysis
    A Next-Gen Sequencing Software Workflow for Cancer Gene Panel...
    DNASTAR offers an integrated suite of software for assembling and analyzing sequence data from all major next-generation sequencing platforms. The software supports a variety of key workflows...
    Speaker: Kerri Phillips
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    8
    OCT 29, 2014 | 9:00 AM
    What's wrong with biomarker development for cancer
    What's wrong with biomarker development for cancer
    Although robust and clinically meaningful biomarkers are key to achieving the current vision for precision (molecularly based), cancer medicine (patient stratification, early diagnosis, drug...
    Speaker: Anna Barker, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    OCT 29, 2014 | 9:00 AM
    Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
    Reading and disrupting the histone code with chemical agents:...
    Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
    Speaker: Fraser Hof, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    7
    OCT 29, 2014 | 7:30 AM
    Making Clinical NGS possible
    Making Clinical NGS possible
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
     
     
  • OCT 29, 2014 | 7:30 AM
    Targeting the oncogene eIF4E in leukemia reveals a new form of drug resistance
    Targeting the oncogene eIF4E in leukemia reveals a new form of...
    The eukaryotic translation initiation factor eIF4E is an oncogene elevated in an estimated 30% of cancers. The traditional view is that eIF4E drives proliferation and survival by increasing t...
    Speaker: Katherine LB Borden, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    40
    OCT 29, 2014 | 7:30 AM
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics and Target Discovery in Oncology
    Antibody-based Proteomics: Fast-Tracking Molecular Diagnostics...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision-making. An...
    Speaker: Darran O'Connor, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    OCT 24, 2014 | 12:00 PM
    What to Do About Flu in 2014
    What to Do About Flu in 2014
      Influenza is a major clinical and public health issue.  Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
    Speaker: Sheldon Campbell M.D. Ph.D. F.C.A.P.
    Sponsored By: Alere, Alere
    36
    OCT 14, 2014 | 1:00 AM
    Aggregation Analysis and Beyond: Analytical Ultracentrifugation in the Biopharmaceutical Industry
    Aggregation Analysis and Beyond: Analytical Ultracentrifugation...
      AUC sedimentation velocity (SV) has a longstanding reputation as being the gold standard for the matrix free quantification of aggregates in biopharmaceuticals. The continuous c(S) ...
    Speaker: Alexander Bepperling, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    30
    SEP 25, 2014 | 8:00 AM
    Grow your LC-MS research and forensic lab profitability with cost-effective analytical workflows
    Grow your LC-MS research and forensic lab profitability with cost-effective...
      This webinar presents LC-MS workflows for cost-effective research and forensic laboratory operation. The workflows, enabled by simple sample preparation coupled with rapid analysis ...
    Speaker: Joseph Di Bussolo, PhD
    Sponsored By: Thermo Fisher Scientific, Thermo Fisher Scientific
    16
     
     
  • SEP 24, 2014 | 3:00 PM
    Site-directed ligand discovery for cryptic sites and other challenging targets
    Site-directed ligand discovery for cryptic sites and other challenging...
    Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
    Speaker: Michelle Arkin, PhD
    Presented at: Advances in Drug Discovery and Development
    20
    SEP 24, 2014 | 2:00 PM
    Targeting Lysine Acetylation in Cancer
    Targeting Lysine Acetylation in Cancer
    Master regulatory transcription factors localize to the genome in a manner influenced by chromatin accessibility and influencing global chromatin structure. With an interest in understanding...
    Speaker: Jay Bradner, MD
    Presented at: Advances in Drug Discovery and Development
    18
    SEP 24, 2014 | 1:00 PM
    The VCNDD: CNS Drug Discovery in Academia
    The VCNDD: CNS Drug Discovery in Academia
    This lecture will provide an overview of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD), focusing on how an Academic Drug Discovery Center was established and is maintained. I...
    Speaker: Craig W. Lindsley, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    6
    SEP 24, 2014 | 12:00 PM
    The Accurate Prediction of Ligand Binding Free Energies
    The Accurate Prediction of Ligand Binding Free Energies
    In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
    Speaker: Mark Murcko, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    22
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