Clinical Pharmacology: Clinical pharmacology is the study of drugs in humans. It has a broad scope, from the discovery of new target molecules, to the effects of drug usage in whole populations. Clinical Pharmacology, in theory, has been practiced for centuries through observing the effects of herbal remedies and early drugs on humans. Most of this work was done through trial and error. Since that discovery clinical pharmacology has expanded to be a multidisciplinary field and has contributed to the understanding of drug interaction, therapeutic efficacy and safety in humans.
Case Example: University of Michigan Chemical Pathology LaboratoryEvery laboratory wants to achieve the highest quality possible and meet its commitment to deliver timely results. However...
Human papillomavirus (HPV) is the primary cause of cervical cancer and more than 100 types of HPV have been identified. Detection of HPV from cervical samples is associated with a 250 times...
Governments, pathology providers, and clients relying on pathology reports face increasing conflict between burgeoning costs versus demands for service innovation. The health industry has bee...
Chronic pain has continued to grow as a public health concern, now affecting more than 116 million people in the United States. It is the leading cause of disability among American workers. L...
Interest in vitamin D status remains high amongst the public and medical profession alike stimulating a surge in requests for clinical laboratories to measure patient serum 25-hydroxyvitamin...
The regulation of molecular testing continues to grow in complexity, in terms of the oversight by FDA, coverage determinations by Medicare contractors, and the payment amounts established by...
Blood culture contamination is a huge problem in the hospital. If strict aseptic technique is not used, patients can be treated unnecessarily, leading to complications from intravenous antimi...
Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
Guidelines for physicians treating pain patients with chronic opioid therapy recommend the patients be monitored for the presence of their prescribed medications. In addition, it is often rec...
Early infantile rickets is the least appreciated form of this ancient disease of children. Although it is usually subclinical, the high prevalence recently reported at autopsy (87% < 1 yea...
While the "Jolie effect" has refocused attention on the central role of BRCA gene analyses in the diagnosis and prevention of hereditary breast and ovarian cancer, there is a global disparity...
Six-Sigma quality is defined as 3.4 (or fewer) defects per million opportunities (DPMO). Achieving Six-Sigma quality in a clinical laboratory is extremely difficult. This presentation will sh...
Variability of vitamin D results remains a hot topic today as more options are available to laboratories. This webinar examines how clinical and analytical factors such as vitamin D binding...
For the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology -- if it is negative, women are rescreen in three years and if po...
Due to the large increase in the number and complexity of clinical laboratory tests, optimal use of laboratory testing services has presented many challenges. The Clinical Laboratory Integrat...
Parkinsons disease is the most common neurodegenerative movement disorder. Over the past few years, studies have identified a number of genes that cause or contribute to the pathogenesis of t...
ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is commonly recognized that technicians are the backbone of a successful animal research program. Unfortunately, the invisible contributions that they make as well as the valuable high lev...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
Case Example: University of Michigan Chemical Pathology LaboratoryEvery laboratory wants to achieve the highest quality possible and meet its commitment to deliver timely results. However...
Human papillomavirus (HPV) is the primary cause of cervical cancer and more than 100 types of HPV have been identified. Detection of HPV from cervical samples is associated with a 250 times...
Governments, pathology providers, and clients relying on pathology reports face increasing conflict between burgeoning costs versus demands for service innovation. The health industry has bee...
Chronic pain has continued to grow as a public health concern, now affecting more than 116 million people in the United States. It is the leading cause of disability among American workers. L...
Interest in vitamin D status remains high amongst the public and medical profession alike stimulating a surge in requests for clinical laboratories to measure patient serum 25-hydroxyvitamin...
The regulation of molecular testing continues to grow in complexity, in terms of the oversight by FDA, coverage determinations by Medicare contractors, and the payment amounts established by...
Blood culture contamination is a huge problem in the hospital. If strict aseptic technique is not used, patients can be treated unnecessarily, leading to complications from intravenous antimi...
Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
Guidelines for physicians treating pain patients with chronic opioid therapy recommend the patients be monitored for the presence of their prescribed medications. In addition, it is often rec...
Early infantile rickets is the least appreciated form of this ancient disease of children. Although it is usually subclinical, the high prevalence recently reported at autopsy (87% < 1 yea...
While the "Jolie effect" has refocused attention on the central role of BRCA gene analyses in the diagnosis and prevention of hereditary breast and ovarian cancer, there is a global disparity...
Six-Sigma quality is defined as 3.4 (or fewer) defects per million opportunities (DPMO). Achieving Six-Sigma quality in a clinical laboratory is extremely difficult. This presentation will sh...
Variability of vitamin D results remains a hot topic today as more options are available to laboratories. This webinar examines how clinical and analytical factors such as vitamin D binding...
For the last 60 years the primary method of preventing cervical cancer in both the U.S. and Europe has been cervical cytology -- if it is negative, women are rescreen in three years and if po...
Due to the large increase in the number and complexity of clinical laboratory tests, optimal use of laboratory testing services has presented many challenges. The Clinical Laboratory Integrat...
Parkinsons disease is the most common neurodegenerative movement disorder. Over the past few years, studies have identified a number of genes that cause or contribute to the pathogenesis of t...
ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
It is commonly recognized that technicians are the backbone of a successful animal research program. Unfortunately, the invisible contributions that they make as well as the valuable high lev...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...