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Chromosome segregation
Sister chromatids, identical chromatids joined by a centromere, can be formed during DNA replication of when homologous chromosomes are paired. In nucleated cells (eukaryotes), chromosome segregation is a biological process occurring in mitosis and meiosis where two sister chromatids separate. Following separation, the individual chromatids travel to opposite sides of the nucleus.
JUL 29, 2020 | 1:00 PM
The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
JUN 03, 2020 | 2:00 AM
Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
JUN 03, 2020 | 12:00 AM
Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
FEB 27, 2019 | 10:30 AM
Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...
AUG 21, 2013 | 2:00 PM
C.E. CREDITS
The human species is particularly prone to chromosome segregation errors during maternal meiosis in the egg and during post zygotic mitosis in the preimplantation embryo. In fact, aneuploidy...
JUN 03, 2020 | 12:00 AM
Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
FEB 27, 2019 | 10:30 AM
Recent clinical successes in cancer genome-inspired personalized medicine have been a major breakthrough in drug discovery. However, 98% of the patients have an incomplete therapeutic respons...