The brain: is the organ located in the head and serves as the center of the nervous system in all vertebrate. The brain is the most complex organ in a vertebrate's body and is close to the sensory organs for senses such as vision.
Somatic mutations that arise during development are increasingly recognized as contributors to neurodevelopmental disease. One challenge has been to determine how mosaic mutations contribute...
Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
Over the past few years there has been an increased interest in the role of cannabis for treating medical conditions. Attitude towards cannabis has evolved rapidly with the expanding legaliz...
As pharmaceutical companies have reduced or eliminated neuroscience drug development due to high costs and low approval rates, the economic and healthcare burden of CNS disorders in the Unit...
Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
More than 50,700 Americans died of opioid overdose in 2019, and more than 1.6 million Americans live with addiction to opioids. Moreover, more than 50 million Americans suffer from chronic p...
The opioid crisis is a uniquely American challenge. Many factors catalyzed this national nightmare and others continue to fuel it. This presentation delves into some of the major contributor...
Substance use disorder (SUD) remains a highly stigmatized medical condition in the US. One of the most effective methods of treatment for SUD, specifically for opioid use disorder and alcoho...
Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
As one of the few evidence-based treatments shown to decrease mortality, buprenorphine use has grown in the United States and abroad. Buprenorphine is a first line option for opioid use diso...
The opioid crisis erupted from a tragic convergence of factors from the private and public sectors. Changing sensibilities on opioid use and abuse, perspectives on addiction and recovery, be...
Urine drug testing has become an essential part of the management of patients with chronic pain. Testing provides objective information regarding drug compliance, diversion, and abuse to med...
Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
Somatic mutations that arise during development are increasingly recognized as contributors to neurodevelopmental disease. One challenge has been to determine how mosaic mutations contribute...
Many diseases show sex differences in incidence or progression, suggesting that one sex has inherent biological factors that protect from or exacerbate disease. Historically the root causes...
Over the past few years there has been an increased interest in the role of cannabis for treating medical conditions. Attitude towards cannabis has evolved rapidly with the expanding legaliz...
As pharmaceutical companies have reduced or eliminated neuroscience drug development due to high costs and low approval rates, the economic and healthcare burden of CNS disorders in the Unit...
Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
More than 50,700 Americans died of opioid overdose in 2019, and more than 1.6 million Americans live with addiction to opioids. Moreover, more than 50 million Americans suffer from chronic p...
The opioid crisis is a uniquely American challenge. Many factors catalyzed this national nightmare and others continue to fuel it. This presentation delves into some of the major contributor...
Substance use disorder (SUD) remains a highly stigmatized medical condition in the US. One of the most effective methods of treatment for SUD, specifically for opioid use disorder and alcoho...
Learning Objectives: 1. Discuss the disease state model of substance use disorder 2. Discuss the evidence surrounding common misconceptions regarding substance use disorder...
As one of the few evidence-based treatments shown to decrease mortality, buprenorphine use has grown in the United States and abroad. Buprenorphine is a first line option for opioid use diso...
The opioid crisis erupted from a tragic convergence of factors from the private and public sectors. Changing sensibilities on opioid use and abuse, perspectives on addiction and recovery, be...
Urine drug testing has become an essential part of the management of patients with chronic pain. Testing provides objective information regarding drug compliance, diversion, and abuse to med...
Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) became a tool to diagnose infectious d...
Sepsis is a life-threatening condition that is caused by the immune system’s inability to respond appropriately to an infection. How sepsis can change the gut microbiome in ways that a...
Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
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