Bioinformatics: an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combines computer science, statistics, mathematics, and engineering to analyze and interpret biological data.
Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
Targeted therapies for cancer are increasingly being developed as an alternative for, and in addition to, immunotherapy. Altered tumor signaling can be exploited to single-out cancer cells f...
Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
Concerns about the quality of published animal research include inefficient or flawed study design, inappropriate statistical analysis and incomplete reporting. The ARRIVE guidelines were de...
DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...
Inherent in research, is the simplification of a complex world into a testing space to explore cause and effect. Across preclinical research, questions are being raised on the testing space...
In the course of the so-called reproducibility crisis, various sources of poor reproducibility of animal research have been identified, including a lack of scientific rigor, low statistical...
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some of way...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimiz...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
Targeted therapies for cancer are increasingly being developed as an alternative for, and in addition to, immunotherapy. Altered tumor signaling can be exploited to single-out cancer cells f...
Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcome. It is expected to be the leading cause of cancer-related death in 2030. The unique microe...
B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
B-cell lymphomas and leukemias originate from the malignant transformation and proliferation of one or a small number of B cells. Since each B-cell expresses distinct B-cell receptors (BCRs)...
Concerns about the quality of published animal research include inefficient or flawed study design, inappropriate statistical analysis and incomplete reporting. The ARRIVE guidelines were de...
DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
The justification of sample size is one of the hardest sections of a proposal an IACUC (ethical review board) has to assess, yet is arguably one of the most important (1). This is a key oppo...
Inherent in research, is the simplification of a complex world into a testing space to explore cause and effect. Across preclinical research, questions are being raised on the testing space...
In the course of the so-called reproducibility crisis, various sources of poor reproducibility of animal research have been identified, including a lack of scientific rigor, low statistical...
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Digital technology is improving the speed and accuracy of all the world’s work processes and activities, the including the research vivarium. This presentation will address some of way...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimiz...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test...
Tuberculosis (TB) is the No.1 cause of death due to a single infectious agent in the world today. According to the global report from World Health Organization, one third of world population...
Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
Animal welfare is the most important issue in any in vivo laboratory. The ability to detect and intervene in cases where the conditions of animals may be deteriorating as well as the ability...
DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...