Bioenergetics is the branch of Biochemistry focused on studying how cells transform energy, such as how adenosine triphosphate (ATP) is produced, consumed, and stored in biological organisms.
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two m...
Immuno-Oncology & Cancer Biology The rapid development of immuno-oncology therapies has transformed the cancer treatment landscape. Discovering safe, potent, and persistent immune cell p...
Immuno-Oncology & Cancer Biology The rapid development of immuno-oncology therapies has transformed the cancer treatment landscape. Discovering safe, potent, and persistent immune cell p...