Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that ......
In clinical laboratory settings, tests for coagulation factors are regularly run to test for inherited or acquired deficiencies in patients suspected of ongoing bleeding risk. Available test...
Labroots and the Cell Planning Committee are pleased to announce the 7th Annual Event in the Cell Biology Virtual Event Series, providing an opportunity to discuss recent discoveries....
Extracellular vesicles (EVs) are lipid-bilayer enclosed nano-sized vesicles that are released by all cell types and found in all bodily fluids. EVs are emerging as important regulators of bo...
Current methods used to predict safety and efficacy of candidate drugs accounts for as much as 90% failure rate. Approximately 30% of drugs have failed......
The global incidence of cancer is on a steady rise, with a projected annual diagnosis rate of nearly 30 million cases by 2040. Despite this alarming trend, our understanding of the intricate...
The capture of tumor-derived extracellular vesicles (TEVs) by cells in the tumor microenvironment (TME) contributes to metastasis and notably to the formation of the pre-metastatic niche (PM...
In recent years in vivo CNS dosing has gone from being a relatively uncommon modality to one that is fairly standard. However, bringing this administration route into maturity requires an un...
Healthy human red blood cells (RBCs) gradually degrade over their lifespan of ~120 days. However, sickle cells - RBCs from sickle cell disease (SCD) patients - degrade much faster within the...
Acute T-cell mediated rejection (TCMR) is the most frequent complication after liver transplantation (LT), which can affect up to 50% of LT recipients in the first 5-year post-transplant. Li...
Current clinical methods used to identify epithelial ovarian cancer are often too late – when the cancer is at an advanced stage, leaving the patient with limited therapeutic options....
Success stories in the field of cell therapies are making headlines on a daily basis. These achievements involve complex manufacturing processes in which cytokines play a key role. Choosing...
In the United States, over 40,000 transplantations are performed annually. Ensuring post-transplant success requires diligent monitoring of infectious diseases that are associated with a wid...
Clinical laboratories generate most of the objective data on which diagnostic, preventive, and therapeutic decisions are made. By considering the current availability of information analytic...
Small extracellular vesicles (EVs) and Exosomes released by cells, have gained significant interest in biomedical research due to their potential applications in diagnostics and therapeutics...
Tandem Mass Tags (TMT) have revolutionized the field of mass spectrometry by enabling simultaneous identification and quantification of protein expression from multiple samples in a single L...
Efficient protein turnover is essential for cell homeostasis and organ function. Loss of proteostasis is a hallmark of aging, which culminates as a severe reduction in protein turnover rates...
Labroots to host the Microbiology Week Virtual Event Series on September 5-7, 2023. Offering discussions on the global development of treatment for Infectious Diseases....
RNA viruses use a variety of interactions with host proteins to gain entry, to evade immune responses, to promote viral replication, and to promote viral egress and spread. These interaction...
Recombinant cytokines and growth factors are essential components for cell culture. Since they are so widely used, it is worth taking a closer look at them and understand their characteristi...
Borrelia burgdorferi, the causative agent of Lyme disease, cycles between an Ixodes spp. vector and a vertebrate reservoir host, typically small rodents. Humans become infected when they int...
Antimicrobial resistance is an important and pressing challenge for global human health. Several obstacles in understanding, diagnosing, and treating antimicrobial resistance limit our abili...
Helicobacter pylori is the primary cause of 78% of gastric cancer cases, providing an opportunity to prevent cancer by controlling a single bacterial pathogen within the complex gastric micr...
Globally, women are disproportionately affected by sexually transmitted infections (STI) including HIV. The immune system of the female reproductive tract (FRT) balances the unique role of p...
Human respiratory syncytial virus (RSV) remains a significant public health concern, particularly for vulnerable populations such as infants, young children, and immunocompromised individua...
Human skin is characterized by a limited number of phyla including, Actinomycetota, Bacillota and Pseudomonadota. In particular, Staphylococcus (Bacillota) and Corynebacterium (Actinomycetot...
Emerging viruses like SARS, SARS-CoV-2, MERS-CoV, Hendra, Nipah, West Nile, sin nombre, LuJo, MERS, Powassan, dengue, chikungunya, zika, Ebola, and Marburg pose a growing threat to public he...
Currently established rapid methods for sterility testing of advanced therapy medicinal products (ATMPs) are mostly based on growth-based processes or the detection......
The arenaviruses are an important group of pathogens that includes several agents of severe human disease, with symptoms that include hemorrhagic fever and neurological complications; howeve...
The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified t...
Adjuvant discovery is largely devoted toward the development of vaccines meant to elicit prophylactic humoral immunity. While useful against infectious diseases, this mode of adaptive immuni...