mouse monoclonal IgG2b; TACI Antibody (C-9) is an IgG2b κ mouse monoclonal TACI antibody (also designated TACI antibody) that detects the TACI protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. TACI Antibody (C-9) is available as both the non-conjugated anti-TACI antibody form, as well as multiple conjugated forms of anti-TACI antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The NFAT (nuclear factor of activated T cells) family of transcription factors regulates cytokine expression in T cells through cis-acting elements located in the promoters of the cytokine genes. The NFAT family consists of the cytoplasmic NFAT (NFATc), transcription factors NFATc1, NFATc2, NFATc3 and NFATc4, and nuclear NFAT (NFATn). Each of these transcription factors plays a role in T cell activation. CAML (calcium-signal modulating cyclophilin ligand) has been identified as an activator of NFAT and NF-IL2A when overexpressed in Jurkat cells. CAML has also been shown to activate calcineurin by causing calcium influx. TACI (transmembrane activator and CAML-interactor), a member of the TNF receptor superfamily, was identified based on its capacity to bind to CAML and has been shown to induce activation of NFAT in the presence of CAML.