mouse monoclonal IgG2b; KRR1 Antibody (F-9) is an IgG2b κ mouse monoclonal KRR1 antibody (also designated KRR1 antibody) that detects the KRR1 protein of mouse, rat and human origin by WB, IP, IF and ELISA. KRR1 Antibody (F-9) is available as both the non-conjugated anti-KRR1 antibody form, as well as multiple conjugated forms of anti-KRR1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.