mouse monoclonal IgG2b; Wnt-2b Antibody (C-2) is an IgG2b κ mouse monoclonal Wnt-2b antibody (also designated WNT2B antibody, or WNT13 antibody) that detects the Wnt-2b protein of mouse, rat and human origin by WB, IP, IF and ELISA. Wnt-2b Antibody (C-2) is available as both the non-conjugated anti-Wnt-2b antibody form, as well as multiple conjugated forms of anti-Wnt-2b antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Wnt family of protooncogenes consists of at least 13 known members which encode secreted signaling proteins that are involved in oncogenesis and several other developmental processes, such as regulation of cell fate and embryogenesis. Wnt-2b (wingless-type MMTV integration site family, member 2B), also known as WNT13 or XWNT2, is a 391 amino acid protein that is secreted into the extracellular matrix and belongs to the Wnt family. Expressed as two isoforms, the first of which is present primarily in adult tissues and the second of which is present primarily in fetal tissues, Wnt-2b functions as a ligand for transmembrane receptor proteins and is thought to play a role in tissue differentiation and development. Wnt-2b is expressed in a variety of cancer cell lines, suggesting a role in tumorigenesis.