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    Follow

    Major Histocompatibility Complex (MHC)

    Major histocompatibility complex (MHC) is a collection of genes involved in immunological recognition of self. It is necessary for cell self-recognition and the prevention of the immune system targeting its own cells.

    Trending News

    • JUL 29, 2024
      Microbiology
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      Influenza Viruses May Have an Alternate Route Into Cells
      The H5N1 avian influenza is highly pathogenic and has been  devastating bird populations worldwide. It continues to ...
      Written By: Carmen Leitch
      3
      SEP 26, 2023
      Immunology
      Technical Note: MHC-Peptide Exchange Technology Explained
      Technical Note: MHC-Peptide Exchange Technology Explained
      Published by Beata Boczkowska, Ph.D.  Understanding how major histocompatibility complex class (MHC) molecules ...
      Sponsored By: MBL International
      10
      AUG 17, 2023
      Technology
      Machine Learning Advances Personalized Cancer Vaccines via BigMHC
      Machine Learning Advances Personalized Cancer Vaccines via BigMHC
      A recent study published in Nature Machine Intelligence examines a novel deep-learning method known as BigMHC, which can ...
      Written By: Laurence Tognetti, MSc
      8
      OCT 10, 2022
      Cancer
      Experimental Drug Can Create Targets for Cancer-Killing Drugs
      Experimental Drug Can Create Targets for Cancer-Killing Drugs
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      APR 26, 2022
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      Unraveling the Mystery of an Immune Cell Checkpoint
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      2
      DEC 30, 2021
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      We still don't know exactly what causes multiple sclerosis (MS), or many other disorders that involve inflammation in th ...
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      2
      OCT 19, 2021
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      Mouse Fathers Passed Immunity Onto Offpsring After Infection
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      SEP 06, 2021
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      SEP 14, 2020
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      The Immune System Can Kill HIV with a Helper Molecule
      The Immune System Can Kill HIV with a Helper Molecule
      HIV attacks the human immune system's CD4 cells, a major player in the body's defense against pathogens.
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      1
      SEP 11, 2020
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      Study Reveals Tumor Defense Mechanism... And How to Beat It
      Study Reveals Tumor Defense Mechanism... And How to Beat It
        P53 is an infamous process gene at the core of the development of tumors.  When P53  functional, it pau ...
      Written By: Amanda Mikyska
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      MAY 14, 2020
      Cancer
      New hope for immunotherapy for pediatric brain cancer
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      Pediatric brain cancer is an especially tough pill to swallow. While one in four children does not survive medulloblasto ...
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      DEC 14, 2019
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      Learning More About How Gene Variants Impact Cystic Fibrosis
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      1
      NOV 12, 2018
      Neuroscience
      Role Of Choroid Plexus Protein Klotho In Aging
      Role Of Choroid Plexus Protein Klotho In Aging
      Inflammaging, describes the increase in an inflammatory alteration in the brain, due to aging and predicts the morbidity ...
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      OCT 14, 2018
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      The Stem of Cancer
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      Scientists reveal a pathway involved in cancer cell ability to act as stem cells
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      AUG 15, 2018
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      JUL 16, 2018
      Immunology
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      2
      FEB 21, 2017
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      Human immunodeficiency virus, notoriously known as HIV, appears untouchable by the immune system, resulting in millions ...
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      OCT 03, 2016
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      Why can the immune system recognize and attack primary tumors but not metastatic tumors? Researchers from the University ...
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      3
      MAY 12, 2016
      Immunology
      "Hide and Seek" Between Cancer and Immune Cells
      "Hide and Seek" Between Cancer and Immune Cells
      Cancer cells are mutated cells that grow abnormally. Cytotoxic T cells of the immune system are designed and developed t ...
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      1
      FEB 06, 2016
      Immunology
      How the Herpes Virus Evades the Immune System
      How the Herpes Virus Evades the Immune System
      Herpes simplex 1 virus, the microscopic pathogen notoriously remembered for its production of painful and unappealing co ...
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      4
      APR 22, 2015
      Neuroscience
      Kissing: A Scientific Frontier Worth Exploring
      Kissing: A Scientific Frontier Worth Exploring
      Lips are the most exposed erogenous zone, which makes kissing feel very good.

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      3
    JUL 29, 2024
    Microbiology
    Influenza Viruses May Have an Alternate Route Into Cells
    Influenza Viruses May Have an Alternate Route Into Cells
    The H5N1 avian influenza is highly pathogenic and has been  devastating bird populations worldwide. It continues to ...
    Written By: Carmen Leitch
    3
    SEP 26, 2023
    Immunology
    Technical Note: MHC-Peptide Exchange Technology Explained
    Technical Note: MHC-Peptide Exchange Technology Explained
    Published by Beata Boczkowska, Ph.D.  Understanding how major histocompatibility complex class (MHC) molecules ...
    Sponsored By: MBL International
    10
    AUG 17, 2023
    Technology
    Machine Learning Advances Personalized Cancer Vaccines via BigMHC
    Machine Learning Advances Personalized Cancer Vaccines via BigMHC
    A recent study published in Nature Machine Intelligence examines a novel deep-learning method known as BigMHC, which can ...
    Written By: Laurence Tognetti, MSc
    8
    OCT 10, 2022
    Cancer
    Experimental Drug Can Create Targets for Cancer-Killing Drugs
    Experimental Drug Can Create Targets for Cancer-Killing Drugs
    Immunotherapies continue to expand the cancer treatment landscape, providing new and exciting approaches to treat tumors ...
    Written By: Katie Kokolus
    4
    APR 26, 2022
    Immunology
    Unraveling the Mystery of an Immune Cell Checkpoint
    Unraveling the Mystery of an Immune Cell Checkpoint
    The immune system can get tired when it has to fight against a chronic infection or a disease like cancer. Exhausted T c ...
    Written By: Carmen Leitch
    2
     
     
  • DEC 30, 2021
    Cell & Molecular Biology
    Researchers Discover Immune Cell Subtype Linked to MS and Neuroinflammation
    Researchers Discover Immune Cell Subtype Linked to MS and Neuroinflammation
    We still don't know exactly what causes multiple sclerosis (MS), or many other disorders that involve inflammation in th ...
    Written By: Carmen Leitch
    2
    OCT 19, 2021
    Cell & Molecular Biology
    Mouse Fathers Passed Immunity Onto Offpsring After Infection
    Mouse Fathers Passed Immunity Onto Offpsring After Infection
    Parents pass their genes on to their children. But they can pass down other things too with epigenetic marks, chemical t ...
    Written By: Carmen Leitch
    2 1
    SEP 06, 2021
    Cancer
    A New Biomarker to Personalize Breast Cancer Therapy
    A New Biomarker to Personalize Breast Cancer Therapy
    The American Cancer Society estimates that over 280,000 women in the United States will be diagnosed with breast cancer ...
    Written By: Katie Kokolus
    5
    SEP 14, 2020
    Microbiology
    The Immune System Can Kill HIV with a Helper Molecule
    The Immune System Can Kill HIV with a Helper Molecule
    HIV attacks the human immune system's CD4 cells, a major player in the body's defense against pathogens.
    Written By: Carmen Leitch
    1
    SEP 11, 2020
    Immunology
    Study Reveals Tumor Defense Mechanism... And How to Beat It
    Study Reveals Tumor Defense Mechanism... And How to Beat It
      P53 is an infamous process gene at the core of the development of tumors.  When P53  functional, it pau ...
    Written By: Amanda Mikyska
    1
     
     
  • MAY 14, 2020
    Cancer
    New hope for immunotherapy for pediatric brain cancer
    New hope for immunotherapy for pediatric brain cancer
    Pediatric brain cancer is an especially tough pill to swallow. While one in four children does not survive medulloblasto ...
    Written By: Kathryn DeMuth Sullivan
    2
    DEC 14, 2019
    Genetics & Genomics
    Learning More About How Gene Variants Impact Cystic Fibrosis
    Learning More About How Gene Variants Impact Cystic Fibrosis
    Cystic fibrosis is caused by a genetic mutation, but small changes other genes appear to influence the severity of the d ...
    Written By: Carmen Leitch
    1
    NOV 12, 2018
    Neuroscience
    Role Of Choroid Plexus Protein Klotho In Aging
    Role Of Choroid Plexus Protein Klotho In Aging
    Inflammaging, describes the increase in an inflammatory alteration in the brain, due to aging and predicts the morbidity ...
    Written By: Aswini Kanneganti
    1
    OCT 14, 2018
    Immunology
    The Stem of Cancer
    The Stem of Cancer
    Scientists reveal a pathway involved in cancer cell ability to act as stem cells
    Written By: Nicholas Breehl
    1
    AUG 15, 2018
    Immunology
    Female vs. Male: The Immune Response
    Female vs. Male: The Immune Response
    There is a genetic sexual conflict in the immune system, with females showing high variation in central genes compared t ...
    Written By: Caitlin Williams
    2
     
     
  • JUL 16, 2018
    Immunology
    T cells and the Need for Speed
    T cells and the Need for Speed
    A recent study has shown that T cell receptors are dispersed across the T cell surface, as opposed to clustered, to allo ...
    Written By: Caitlin Williams
    2
    FEB 21, 2017
    Immunology
    HIV Plays "Hide and Seek" With Our Immune System
    HIV Plays "Hide and Seek" With Our Immune System
    Human immunodeficiency virus, notoriously known as HIV, appears untouchable by the immune system, resulting in millions ...
    Written By: Kara Marker
    3
    OCT 03, 2016
    Immunology
    Metastatic Tumors Outsmart the Immune System
    Metastatic Tumors Outsmart the Immune System
    Why can the immune system recognize and attack primary tumors but not metastatic tumors? Researchers from the University ...
    Written By: Kara Marker
    3
    MAY 12, 2016
    Immunology
    "Hide and Seek" Between Cancer and Immune Cells
    "Hide and Seek" Between Cancer and Immune Cells
    Cancer cells are mutated cells that grow abnormally. Cytotoxic T cells of the immune system are designed and developed t ...
    Written By: Kara Marker
    1
    FEB 06, 2016
    Immunology
    How the Herpes Virus Evades the Immune System
    How the Herpes Virus Evades the Immune System
    Herpes simplex 1 virus, the microscopic pathogen notoriously remembered for its production of painful and unappealing co ...
    Written By: Kara Marker
    4
     
     
  • APR 22, 2015
    Neuroscience
    Kissing: A Scientific Frontier Worth Exploring
    Kissing: A Scientific Frontier Worth Exploring
    Lips are the most exposed erogenous zone, which makes kissing feel very good.

    Written By: Robert Woodard
    3
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