Follow a comprehensive curation of novel and significant discoveries in the fields of genetics and genomics by watching these webinars. Highlighted areas of interest in the fields of genetics and genomics include epigenetics, molecular genetics, hereditary disease, clinical genetics, population genetics, etc.
The defining characteristic of Companion Diagnostics (CDx) is that their use is associated with selection of a therapy or other medical intervention....
Many oncology patients do not receive the most effective targeted treatments because of challenges associated with implementation of a personalized medicine approach. Despite a lengthy histo...
Genomics has had rapid implementation over the past decade, with recent growth in application in oncology, mental health, maternal fetal medicine, solid organ transplantation, and more. Much...
Learning Objectives: 1. Describe alternative (non-B) DNA structures, how prevalent are they and what are their biological implications? 2. Explain why non-B DNA structures might be relevant...
Experience the Revolution of DNA Polymerase Technology: Choosing the Best DNA Polymerase for Efficient PCR Workflows. PCR has revolutionized modern molecular biology, but its success would n...
The Genomes2People Research Program (G2P), led by Robert Green at Brigham and Women’s Hospital, the Broad Institute, Ariadne Labs, and Harvard Medical School, conducts research to acce...
The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those...
With the health economic benefits of genetic testing clear, testing is becoming more accessible, which means constantly increasing throughput requirements for already stretched genomics......
Approximately 13% of the human genome at certain motifs have the potential to form non-canonical (non-B) DNA structures (e.g. G-quadruplexes, cruciforms, and Z-DNA), which regulate......
In the field of oncology, the ability to select cells from a specific location or region within a tissue and analyze each discrete genome allows for the understanding of tumor heterogeneity....
Learning Objectives: 1. Discuss the conceptual limitations of the term, "population" as applied to human genomics. 2. Explain the main difference(s) between "race", "...
Accurate prediction of anticancer drug efficacy on each patient’s cancer before the initiation of therapy has the potential to significantly reduce the treatment burden and enhance cli...
Long-read sequencing was declared the method of the year for 2022 and, indeed, has fully arrived on the computational biology scene. Specifically, Oxford Nanopore Sequencing technology has e...
The All of Us (AoU) initiative aims to enhance personalized medical care by sequencing the genomes of over one million Americans of diverse ethnic backgrounds. To improve sequencing accuracy...
Silk is essential to the life histories of more than 800,000 species across the arthropod tree of life. Humans have harnessed the ability of a handful of these for use in the sericulture ind...
Genomic testing based on chromosome microarray (CMA) and Next Generation Sequencing (NGS) revolutionized clinical genetics. That said, microarray, targeted panel, exome and generic whole gen...
It has been publicly stated by the CDC that one in 5 Americans had an STI in 2018 and costs our healthcare system roughly $16 billion in direct medical costs. Routine sexually transmitted inf...
Our understanding of the genetic basis of disease has been rapidly advancing thanks to major technological advances in genomic sequencing and data analysis. Yet the majority of individuals w...
Learning Objectives: 1. Discover how Genetics is not the major determinant of chronic diseases and cancers; human microbiome and nutrition heavily contribute to their onset and progression....
Spinal muscular atrophy (SMA) is a devastating neuromuscular disease caused by mutations in the SMN1 gene that reduce survival motor neuron (SMN) protein expression. Despite progress in the...
Learning Objectives: 1. List types of sequencing and genomics methods. 2. List several methods for epigenome engineering. 3. Describe the genomic changes that occur in a spacecraft and in ast...
The current version of the human reference genome, GRCh38, contains a number of errors including 1.2 Mbp of falsely duplicated and 8.04 Mbp of collapsed regions. These errors impact the vari...
Date: April 26, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the...
Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
Date: April 20, 2023 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) he study of human evolution. A decade ago, his team managed to sequence the Neanderthal and Denisovan genomes which resul...
The defining characteristic of Companion Diagnostics (CDx) is that their use is associated with selection of a therapy or other medical intervention....
