Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms. Remain up to date on recent discoveries and revelations through these webinars.
MicroRNAs (miRs) are small non-coding RNAs whose expression is altered in several types of human cancers. Recent evidence supports their inter-cellular transfer through extracellular vesicle...
Extracellular vesicles provide a tool to measure tumour characteristics in blood, at various stages of cancer development. We have extensively used multiplex RNA bead-based assays (Quantigen...
Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
Since 1993, Gibco™ B-27™ Supplement and Neurobasal™ Medium has been the trusted standard for a variety of neuronal culture applications, with citations in more than 11,000 p...
Deriving deeper biological insight & improving productivity in immune-cell biologyThe most common in vitro methods for immunologists to analyze cells of the immune system are flow cyt...
The majority of patients with advanced NSCLC do not respond to monotherapy with PD-1 axis inhibition, and more robust predictive biomarkers are needed. In this study, we assessed tumor sampl...
Neuroinflammation has been implicated as a factor in alcohol-induced neurodegeneration, but the role of the neuroimmune system in alcohol consumption has only recently come to the forefront....
α-synuclein (-syn) is a small presynaptic protein linked to the pathogenesis of Parkinson’s disease (PD) and related disorders, collectively called synucleinopathies. Phosphoryl...
Thinking about a starting a job search? Join us to listen to some tips to help you prepare for starting a successful career/job search. Topics covered: Resume Writing tips, Preparing fo...
I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
Vaccines have played a major role in protecting human health as one of the key means of controlling infectious diseases. More than 20 high-risk diseases can be currently prevented through va...
Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
After a brief definition of terms (what are bioplastics?), this lecture will discuss various material and application examples for biobased and/or biodegradable plastics. An overview on the...
Heterotetrameric adaptor protein (AP) complexes play key roles in protein sorting and transport vesicle formation in the endomembrane system of eukaryotic cells. One of these complexes, AP-4...
Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphati...
Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
Biomedical researchers are increasingly using advanced human cell models for translational biology and therapeutic discovery studies. These include patient-specific samples, cultured micro-ti...
For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
Multi-target screening can offer great insight into the genetic pathways in drug resistance and disease. RNAi and the fast pace of CRISPR technology development has brought sophisticated opt...
Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
MicroRNAs (miRs) are small non-coding RNAs whose expression is altered in several types of human cancers. Recent evidence supports their inter-cellular transfer through extracellular vesicle...
