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Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
The public health burden of Treatment Resistant Depression (TRD) has prompted clinical trials of deep brain stimulation (DBS) that have, unfortunately, produced inconsistent outcomes. Potent...
Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
Complex recombinant protein biologics, such as monoclonal antibodies and coagulation factors, are key components of today’s biopharmaceutical industry. There are many effective paths fo...
The success in the solving cases is based upon a system that emphasizes teamwork, from scene; recognition, collection, preservation, to laboratory; examination, identification , individualiz...
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its chara...
It has been estimated that every human being carries ~20 rare “natural human gene knockouts”-DNA variants in protein-coding regions of the genome that partially or completely inac...
Our speaker, Wenjie Xu, Ph.D., will present his publication data demonstrating how nCounter® technology can advance your infectious disease research faster and more accurately with unprec...
Core or central laboratory are facing several challenges. First, the management and operations of a successful modern laboratory is a real complex exercise, with multiple pre- and post-analyt...
Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
Joshua Gordon, M.D., Ph.D., Director of the National Institute of Mental Health, will provide an overview of challenges and opportunities in mental health research. Dr. Gordon will present em...
Terpenes are a broad class of chemicals that are found throughout the Cannabis plant that produce the unique aroma and taste of your favorite variety. Cannabis breeders have been selecting f...
My research program focuses on building the technology to generate diverse human cell-types for application in regenerative medicine and drug toxicology testing. While embryonic stem cells (E...
Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
Patient laboratory test results are significantly over-represented in electronic medical records, but significantly under-utilized in research. An important application of laboratory data is...
In 2013, a separate diagnosis of PTSD was introduced into the DSM-V to mitigate the well-known issue of accurately differentiating between PSTD and other psychiatric disorders. In addition t...
Sensorimotor integration is important for the acquisition and performance of motor skills. Here,we show the emergence of neuroplastic changes in the interactions between the motor andsomatose...
In the event of a radiological or nuclear disaster, there will be a need for therapies that can mitigate the acute hematopoietic and gastrointestinal (GI) radiation syndromes expected to dev...
The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
With the passing of the 2018 Farm Bill legalizing hemp, farmers are allowed to grow hemp. Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and...
Advances in DNA sequencing technology are about to transform healthcare. Since completion of the human genome reference sequence ten years ago, there has been a 1-million fold im...
Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
Biomedical research suffers from a translation gap, where most treatments that seem effective when tested on animals turn out not to work in human patients. This is likely due in large part...
Employing a metagenomic search, we identified a family of miniature CRISPR-Cas type V-L systems capable of RNA-guided dsDNA target cleavage without a tracrRNA. A bacterial depletion screen r...
To study cell metabolism, our laboratory has found it exceedingly informative to integrate Agilent Seahorse XF Analyzers with mass spectrometry-based measurements of metabolomics and stable i...
For a plant that has been legal in some states for over 20 years, there has been an attitude that “cannabis never killed anyone.” While we don’t have the necessary rese...