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High resolution surveys of the tumor microenvironment (TME) are needed to obtain a holistic portrait of the genetic, epigenetic, and cellular factors contributing to cancer progression. To t...
Too frequently the investigator will provide “scientific” reasons to justify precluding analgesics from experimental procedures that may involve more than momentary pain, often wi...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
As of March 2021, SARS-CoV-2 has infected 115 million people and caused over 2.56 million deaths. The emergence of mutants associated with changes to transmission of SARS-CoV-2 has shown tha...
Step into the fast-paced world of bioanalysis where laboratories transform into hubs of innovation, continually searching for ways to refine processes, enhance workflows, and remain aligned...
Community acquired pneumonia affects over 5 million Americans and 6 million Europeans annually. Typically 5-10% will be admitted to hospital. It is a condition that more often affects the eld...
Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
In 2017, the Washington State Legislature passed HB 1427, which mandated that boards and commissions for five prescribing professions (dental, medical, nursing, osteopathic, and podiatric) en...
Next-generation sequencing (NGS) has become the most effective tool in the practice of clinical oncology. The technology allows for rapid detection of variants in DNA/RNA simultaneously in a...
Learning Objectives: 1. Understand the antibody discovery protocols in pharmaceutical research 2. Understand the importance of single cell secretion screening protocols 3. Describe lensless...
Drug development is a costly and time consuming process, poor translation of data from pre-clinical studies to the clinic is a major contributor as late-stage drug failure is very expensive....
Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...
In contrast to other countries in Latin America, Peru had been notoriously spared by the global dissemination of carbapenem-resistant Klebsiella pneumoniae (CR-Kp) until recently. Isolated ca...
With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
New insights on the pathogenesis of COVID-19 7:00–7:30 pm PDT Presented By: Olaf Rötzschke, PhD The SIgN Mass Cytometry Platform (MCP) was originally established by Evan Newell, P...
Neuropore Therapies is discovering and developing novel small molecule disease-modifying therapeutics to treat patients with neurodegenerative diseases, including Parkinson’s disease a...
What motivates patients to participate in clinical trials? Discussions most often revolve around potential study participants’ perception of therapeutic benefit. Misconceptions about th...
The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
Over the past few years there has been an increased interest in the role of cannabis for treating medical conditions. Attitude towards cannabis has evolved rapidly with the expanding legaliz...
Healthcare associated infections can be a consequence of a microbiome alteration. Increasingly, treatment and prevention strategies focus on manipulating host microbiota, the two most common...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
In part 2 of this webinar, Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, will reveal new data that illustrates how the Hodges Lab is utilizing the 6-base ge...
Whole genome sequencing of bacterial isolates via next-generation sequencing is becoming a standard approach for clinical microbiology and bio-surveillance labs seeking to conduct outbreak in...
Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
The potential for cognitive bias in forensic evidence interpretation and crime scene investigation continues to receive attention and debate within forensic and academic communities. Startin...