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mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield...
The study of a single cell, the fundamental unit of our complex bodies, has become an important field in cellular biology, and researchers are using single-cell analysis to shed new light on...
Proliferation biomarkers are proteins that are up-regulated in growing cells. Immunological staining of tumor tissue can provide an indication of the aggressivity of the tumor and provide in...
Women experience a variety of unique sexual health issues that are often under appreciated by the general public and even by healthcare providers. Compared to other populations, cisgender wo...
Learning Objectives Identify three ways automation improves cryosectioning techniques Demonstrate three essential elements to obtaining reproducible, high-quality sections with cryosectionin...
Over the course of the COVID-19 pandemic, there has been a dramatic increase in the number and type of diagnostic tests for respiratory viruses. These include targeted molecular assays, smal...
Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, th...
In recognition of World AIDS Day, we invite you to discover the innovative work being done to help end the HIV epidemic in some of the hardest hit areas in India. A diagnosis is the first st...
Pathology Perspective: Discover the critical need for genomic testing in cancer and explore the differences between traditional tissue biopsies and liquid genomic profiling. We'll dive i...
Myelodysplastic Syndrome (MDS) requires a complicated workup that can be supported by Artificial Intelligence (AI). Initial findings using AI have shown that MDS can be preliminarily identif...
Summary: Internal quality control is an integral process of laboratory testing. A clinical laboratory's coagulation quality control (QC) program is a critical component of its quality as...
Assessment for anti-dsDNA antibodies provides some of the most significant challenges in autoantibody serology testing. Anti-dsDNA antibodies are an important biomarker for systemic lupus er...
It is over half a century since haemoglobin A1c (HbA1c) was recognised by medical professionals; the importance of HbA1c to the long term health of people with diabetes was clearly demonstra...
Tissue microarray combines tens to hundreds paraffin-embedded specimens into a single paraffin block. It is a practical and highly effective tool for high-throughput analyses including valid...
Gynecologic cancers account for nearly 40% of all cancer incidence and >30% of all cancer mortality in women worldwide. In recent years, there have been significant advancements in the cl...
For patients with advanced non-small cell lung cancer (NSCLC), tissue samples are typically small biopsies. These samples undergo standard of care evaluation for >10 biomarkers to identif...
Organoids continue to gain traction in drug discovery efforts as they offer a more biologically relevant disease model than traditional approaches. But they aren't without challenges. Jo...
Current clinical methods used to identify epithelial ovarian cancer are often too late – when the cancer is at an advanced stage, leaving the patient with limited therapeutic options....
As the opioid epidemic continues to claim lives and devastate families across the nation and world, we recognize September 21, 2023 as opioid awareness day. Opioids are analgesics with high...
Preanalytical errors and unsuitable samples can account for up to 70% of lab errors. 1 These errors can be attributed to improper specimen collection, specimen transportation, and specimen p...
In clinical laboratory settings, tests for coagulation factors are regularly run to test for inherited or acquired deficiencies in patients suspected of ongoing bleeding risk. Available test...
Current clinical methods used to identify epithelial ovarian cancer are often too late – when the cancer is at an advanced stage, leaving the patient with limited therapeutic options....
Success stories in the field of cell therapies are making headlines on a daily basis. These achievements involve complex manufacturing processes in which cytokines play a key role. Choosing...
In the United States, over 40,000 transplantations are performed annually. Ensuring post-transplant success requires diligent monitoring of infectious diseases that are associated with a wid...
Clinical laboratories generate most of the objective data on which diagnostic, preventive, and therapeutic decisions are made. By considering the current availability of information analytic...
Small extracellular vesicles (EVs) and Exosomes released by cells, have gained significant interest in biomedical research due to their potential applications in diagnostics and therapeutics...
Recombinant cytokines and growth factors are essential components for cell culture. Since they are so widely used, it is worth taking a closer look at them and understand their characteristi...