Per and polyfluoroalkyl substances (PFAS) are chemicals widely used in consumer products and industry due to the unique and desirable chemical properties. Due to widespread usage and environmental persistence, legacy PFAS have been found in drinking and non-potable water in the United States and around the world. These substances, particularly with carbon-chain lengths >7 are bioaccumulative and have been linked to adverse health effects in humans and wildlife. Regulatory lists of PFAS compounds are growing, as are state and local monitoring efforts. Targeted detection techniques for quantifying PFAS in water are important and ideally would both meet the necessary sensitivity and capacity required. We will explore use of the latest QQQ 6495C technology and its ability to push sensitivity lower with more difficult PFAS such as GenX. Methods will be discussed with an emphasis on sensitive high-throughput techniques.
For Research Use Only. Not for use in diagnostic procedures.