Potency Testing & Instrument Configuration

Rapid gradient method optimized for 17 cannabinoids using HPLC-UV
Presented By: Chris Leija, PhD

Let's talk instrument configuration for an ideal LC method
Presented By: Hillel Brandes, PhD

When planning for new method development, an initial consideration should include what instrument is available or intended to be used for the experimentation. This will impact options regarding choice of analytical column. Conversely if a specific type of column is intended, this will influence what instrument is best paired with the column. Given those choices, what follows are other considerations regarding instrument configuration to optimize the chromatographic performance of the selected column. While method development generally addresses aspects of the actual analytical method, this talk will highlight due consideration of optimum instrument configuration to achieve the best chromatographic performance.

High Purity Water: Hints and Tips for Cannabis Analyses
Presented By: Tricia Schnulle

Ultrapure water is highly prone to contamination, e.g., it easily leaches contaminants out of container surfaces and absorbs contamination from the laboratory environment. As ultrapure water is the most-frequently used solvent in any LC-MS laboratory, its purity plays a critical role in analyses. There are a number of high-purity water handling pitfalls that result in degradation of its quality. To help analysts critically evaluate the potential risks involved in poor ultrapure water handling, we will discuss the effect of laboratory environment and long high-purity water storage, the effect of the container material used to collect ultrapure water, the effect of laboratory ware and equipment cleaning, and the effect of poor practices of water purification system usage.