MIMETAS and BioTek Instruments: A Toolbox to Dissect the Vascular Impact of COVID-19

Since the onset of the current pandemic, COVID-19 has been described largely as a respiratory disease.  While the respiratory tract and alveoli are one of the primary sites of infection and pathology, the disease can affect multiple organ systems and displays a broad range of symptoms and sequelae.  Recent data suggest COVID-19 may be a vascular disease, owing to the direct and indirect impacts of the virus, SARS-CoV-2, to the endothelium.  Vasculature can be studied using numerous in vitro models, however, many platforms lack relevant biological and technical attributes, including barrier function, perfusion, high throughput capabilities, and compatibility with imaging and detection instruments.  With MIMETAS’ Organ-on-a-Chip technology and BioTek Automated Imaging and Detection instrumentation, the direct and indirect vascular impacts of viral infection can be studied using a variety of biologically relevant high-throughput three-dimensional models of the endothelium.  This collaborative webinar will provide a toolbox of MIMETAS products and relevant BioTek imaging and detection applications to dissect and improve our understanding of the interplay between SARS-CoV-2 and vasculature.