Lightning fast CE-SDS and cIEF workflows for protein therapeutics characterization with demonstrated high-throughput

In early drug development, lead clone selection requires a large number of clone screening in cell line development. Developability assessment studies also screens many molecules to identify process development issues. Therefore, high-throughput sample analysis is critical for biotherapeutics drug development where high sample input and short timeline is greatly desired with a growing number and wider variety of new drug candidates. Capillary electrophoresis (CE) has demonstrated its relevance in biotherapeutics analysis due to its high separation efficiency and multiple separation mode to assess different characterization attributes such as, purity, stability and charge variants. In this webinar, we will present a lightning-fast CE-SDS workflow and a fast cIEF workflow that are capable of high-throughput analysis of protein therapeutics. The robustness of the workflows is systematically evaluated, demonstrating remarkable reproducibility, accuracy and reliability.

 

Learning Objectives