Full human antibody discovery with Beacon and Harbour Mice®

As one of the earliest partners and the first one in Asia-Pacific region of Berkeley Lights (now Bruker Cellular Analysis), Nona Biosciences has built a state-of-the-art single B cell cloning antibody discovery platform utilizing the Beacon system in combination with our proprietary fully human Harbour Mice® technology. In this talk, besides the usual single B cell cloning workflow, we’ll also share with you case studies on the exploration of 1) single B cell cloning + NGS to expand the throughput, 2) Beacon in-chip assay with overnight cultured or frozen plasma cells, the screening efficiency and diversity coverage, 3) some tips for assay optimization.